Lymphatic mapping and sentinel lymph node detection in women with vaginal cancer

Gynecologic Oncology
Michael FrumovitzCharles F Levenback

Abstract

To determine the patterns of lymphatic drainage from primary vaginal cancers utilizing lymphoscintigraphy and to determine if this clinical information would affect treatment planning. For women with newly diagnosed vaginal cancer, pretreatment lymphatic mapping and sentinel lymph node identification were performed using lymphoscintigraphy. In patients who underwent surgery, sentinel lymph nodes were identified intraoperatively using radiocolloid and patent blue dye. The impact of pretreatment lymphoscintigraphy findings on radiation planning in women who received radiation as initial treatment was noted. Fourteen women were enrolled during the study period. At least 1 sentinel lymph node was identified on pretreatment lymphoscintigraphy in 11 patients (79%). The median number of sentinel nodes found per patient was 2, and bilateral sentinel nodes were found in 6 (55%) of the 11 patients with sentinel nodes identified. Among these 11 patients, 5 (45%) had sentinel nodes identified in the groin only, 4 (36%) had sentinel nodes identified in the pelvis only, and 2 (18%) had sentinel nodes identified in both the groin and the pelvis. No relationship was observed between sentinel lymph node location and primary tumor histologic sub...Continue Reading

Associated Clinical Trials

References

Jan 31, 2004·Gynecologic Oncology·Peter van DamLuc Y Dirix
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Citations

Jan 29, 2009·World Journal of Surgical Oncology·Stephen P PovoskiEdward W Martin
Feb 18, 2012·Gynécologie, obstétrique & fertilité·T GauthierP Morice
Apr 12, 2011·Journal of Surgical Oncology·Stanley P L LeongSukamal Saha
Dec 3, 2013·Gynecologic Oncology·Michael FrumovitzCharles F Levenback
Nov 26, 2010·Obstetrics and Gynecology·Michael FrumovitzPedro T Ramirez
Dec 24, 2013·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Lingfang XiaXiaohua Wu
Nov 2, 2013·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Hermann HertelPeter Hillemanns
Feb 9, 2010·Clinical Nuclear Medicine·Katsuhiro KobayashiIsis W Gayed
Jan 9, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Mikel GorostidiGlauco Baiocchi
Sep 27, 2016·Obstetrics & Gynecology Science·Jae Hoon LeeSang Wun Kim
Mar 2, 2013·Melanoma Research·Charlotte VaysseMartine Delannes
Dec 18, 2019·Histopathology·Elizabeth D Euscher, Anais Malpica
Dec 12, 2020·Minerva ginecologica·Silvia PelligraFrancesco Fanfani
Aug 3, 2021·Abdominal Radiology·Rachel SteinChandana Lall

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