Lymphatic Programing and Specialization in Hybrid Vessels

Frontiers in Physiology
John B Pawlak, Kathleen M Caron

Abstract

Building on a large body of existing blood vascular research, advances in lymphatic research have helped kindle broader investigations into vascular diversity and endothelial plasticity. While the endothelium of blood and lymphatic vessels can be distinguished by a variety of molecular markers, the endothelia of uniquely diverse vascular beds can possess distinctly heterogeneous or hybrid expression patterns. These expression patterns can then provide further insight on the development of these vessels and how they perform their specialized function. In this review we examine five highly specialized hybrid vessel beds that adopt partial lymphatic programing for their specialized vascular functions: the high endothelial venules of secondary lymphoid organs, the liver sinusoid, the Schlemm's canal of the eye, the renal ascending vasa recta, and the remodeled placental spiral artery. We summarize the morphology and endothelial expression pattern of these vessels, compare them to each other, and interrogate their specialized functions within the broader blood and lymphatic vascular systems.

References

Nov 30, 1978·Pflügers Archiv : European journal of physiology·W MollM Voslar
Sep 1, 1992·Experimental Eye Research·T HamanakaT Ishida
Sep 1, 1992·The Journal of Cell Biology·M G LampugnaniE Dejana
May 1, 1991·Cell and Tissue Research·H Takahashi-Iwanaga
Nov 1, 1973·The Journal of Clinical Investigation·E A JaffeR L Nachman
Apr 11, 1995·Proceedings of the National Academy of Sciences of the United States of America·A KaipainenK Alitalo
Jun 1, 1996·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D VrochidesP Heldin
Feb 1, 1997·Endocrine Reviews·N Ferrara, T Davis-Smyth
Dec 31, 1997·The American Journal of Physiology·C PupilliM Serio
Feb 21, 1998·Proceedings of the National Academy of Sciences of the United States of America·M D GunnL T Williams
Mar 21, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A CouvelardJ Y Scoazec
Apr 18, 1998·The Journal of Biological Chemistry·R YoshidaO Yoshie
Feb 26, 1999·The Journal of Cell Biology·S BanerjiD G Jackson
Jun 15, 1999·The Journal of Cell Biology·R V StanG E Palade
Nov 11, 1999·Proceedings of the National Academy of Sciences of the United States of America·R V StanG E Palade
Jun 24, 2000·Molecular and Cellular Biology·X Z HuangD Sheppard
Oct 26, 2001·Mechanisms of Development·Y HerzogG Neufeld
May 10, 2002·The American Journal of Pathology·Ulrike SamulowitzDietmar Vestweber
Oct 4, 2002·Placenta·F Lyall
Nov 2, 2002·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Young-Kwon HongGuillermo Oliver
Nov 26, 2002·Proceedings of the National Academy of Sciences of the United States of America·Simona PodgrabinskaMihaela Skobe
Apr 3, 2003·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Mariappan MuthuchamyDavid Zawieja
Apr 5, 2003·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Thomas L PalloneRex L Jamison
Nov 26, 2003·Investigative Ophthalmology & Visual Science·Makoto AiharaRobert N Weinreb
Dec 12, 2003·Proceedings of the National Academy of Sciences of the United States of America·Masanori HirashimaJanet Rossant
Jan 6, 2004·Nature Reviews. Immunology·Guillermo Oliver
Dec 23, 2004·The Journal of Clinical Endocrinology and Metabolism·Ariane GermeyerNihar R Nayak
May 12, 2005·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Noritoshi NagayaSoichiro Kitamura
Dec 29, 2005·American Journal of Physiology. Renal Physiology·Thomas L Pannabecker, William H Dantzler

❮ Previous
Next ❯

Citations

Dec 3, 2020·Frontiers in Cardiovascular Medicine·Khoa Bui, Young-Kwon Hong
Jun 24, 2021·Nature Reviews. Nephrology·Michael D DonnanSusan E Quaggin
Jul 3, 2021·Biology·Mariela Subileau, Daniel Vittet
Jul 10, 2021·Cellular and Molecular Life Sciences : CMLS·Lionel GillotAgnès Noël
Aug 2, 2021·Trends in Molecular Medicine·Simon StrittTaija Mäkinen

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

© 2021 Meta ULC. All rights reserved