Abstract
Osteopathic practitioners utilize manual therapies called lymphatic pump techniques (LPT) to treat edema and infectious diseases. While previous studies examined the effect of a single LPT treatment on the lymphatic system, the effect of repeated applications of LPT on lymphatic output and immunity has not been investigated. Therefore, the purpose of this study was to measure the effects of repeated LPT on lymphatic flow, lymph leukocyte numbers, and inflammatory mediator concentrations in thoracic duct lymph (TDL). The thoracic ducts of five mongrel dogs were cannulated, and lymph samples were collected during pre-LPT, 4 min of LPT, and 2 hours post-LPT. A second LPT (LPT-2) was applied after a 2 hour rest period. TDL flow was measured, and TDL were analyzed for the concentration of leukocytes and inflammatory mediators. Both LPT treatments significantly increased TDL flow, leukocyte count, total leukocyte flux, and the flux of interleukin-8 (IL-8), keratinocyte-derived chemoattractant (KC), nitrite (NO2(-)), and superoxide dismutase (SOD). The concentration of IL-6 increased in lymph over time in all experimental groups; therefore, it was not LPT dependent. Clinically, it can be inferred that LPT at a rate of 1 pump per sec f...Continue Reading
References
Aug 1, 1990·Clinical Science·A M CruickshankA Shenkin
Jan 1, 1994·Annual Review of Biochemistry·D S Bredt, S H Snyder
Jan 1, 1994·The British Journal of Surgery·M S JakewaysF Carli
Apr 1, 1995·Academic Radiology·C L Witte, M H Witte
Jan 16, 1998·Anesthesia and Analgesia·C W WhittenJ M Lipton
Apr 1, 1997·Nitric Oxide : Biology and Chemistry·M MarzinzigU B Brückner
May 3, 2002·The Journal of Physiology·Anatoliy A GashevDavid C Zawieja
Nov 1, 1963·Circulation·H S MAYERSON
Oct 8, 2003·The Japanese Journal of Physiology·Hideo TsunemotoToshio Ohhashi
Dec 31, 2004·Lymphatic Research and Biology·Waldemar L Olszewski
Jul 1, 2006·The Journal of Physiology·Olga Yu GashevaAnatoliy A Gashev
Oct 16, 2007·Lymphatic Research and Biology·Lisa M HodgeH Fred Downey
Mar 26, 2008·Lymphatic Research and Biology·H Fred DowneyScott T Stoll
Jun 4, 2008·Annals of the New York Academy of Sciences·Stanley G Rockson
Jun 19, 2009·Lymphatic Research and Biology·David C Zawieja
Aug 12, 2009·American Journal of Physiology. Heart and Circulatory Physiology·H Glenn BohlenDave Zawieja
Jul 1, 2008·Journal of Medical Physics·A S PradhanJ L Kim
Feb 11, 2010·Lymphatic Research and Biology·Stanley G Rockson
Mar 23, 2010·Osteopathic Medicine and Primary Care·Donald R NollScott T Stoll
Jun 30, 2010·Lymphatic Research and Biology·Lisa M HodgeH Fred Downey
Sep 25, 2010·Lymphatic Research and Biology·Parna PrajapatiH Fred Downey
Dec 31, 2010·Lymphatic Research and Biology·Jamie B HuffLisa M Hodge
Dec 16, 2011·Experimental Biology and Medicine·Artur SchanderLisa M Hodge
Jan 25, 2012·The American Journal of Medicine·Giuseppe MurdacaFrancesco Boccardo
Sep 15, 2012·International Journal of Osteopathic Medicine : IJOM·Lisa M Hodge
Citations
Mar 26, 2016·Frontiers in Neuroscience·Giandomenico D'AlessandroPietro Cortelli
Jun 20, 2015·Lymphatic Research and Biology·Takaaki SaitoHiroyuki Konno
Mar 23, 2017·Medicine·Diego LanaroGianluca Lista
Nov 27, 2018·The Journal of the American Osteopathic Association·Teresa KilgoreJohn Samies
Apr 28, 2020·The Journal of the American Osteopathic Association·Artur SchanderLisa M Hodge
Jul 14, 2020·The Journal of the American Osteopathic Association·Eric Martinez, David Redding
Jun 28, 2018·The Journal of the American Osteopathic Association·Rudy CastilloLisa M Hodge
Oct 16, 2019·The Journal of the American Osteopathic Association·Hope TobeyBlaise M Costa
Jun 28, 2018·The Journal of the American Osteopathic Association·Danielle FranziniStacey Pierce-Talsma
May 6, 2015·The Journal of the American Osteopathic Association·Lisa M HodgeHollis H King
May 31, 2017·The Journal of the American Osteopathic Association·Christopher Carls, Predrag Krajacic
May 27, 2021·Expert Review of Anti-infective Therapy·Emil LeshoMaryrose Laguio-Vila
Jun 9, 2021·Journal of Orthopaedics·Sergio RigoniMario Scapin
Aug 24, 2021·Curēus·Raymond J Hruby, Eric S Martinez