PMID: 6966181Apr 1, 1980Paper

Lymphoblastic lymphoma/leukemia with convoluted nuclei: the question of its relation to the T-cell lineage studied in 13 patients

Cancer
C BoucheixG Bilski-Pasquier

Abstract

This work is devoted to the analysis of the nature of lymphoblastic lymphoma/leukemia with convoluted nuclei which were initially described by Barcos and Lukes. Ultrastructural, cytochemical, and immunologic features of tumor cells were investigated in patients chosen according to known morphologic criteria. Through results of the E rosette test, the patients were divided into two groups (E+ and E-). In the E+ group, the predominant features were sex (only men), the mediastinal localization, and the focal positivity of the acid phosphatase reaction. Cytotoxicity tests with rabbit antihuman T-lymphocyte anti-serum confirmed the results of the E rosette test in the 3 patients of the E+ group who were tested and were also positive in 2 patients from the E- group (1 of these 2 patients had the characteristics found in the E+ group and can thus be related to this group; the other patient had none of these characteristics). This raises the question of a leukemia arising from a less differentiated T-cell but this interpretation is limited by the specificity of the anti-T-serum. Ultrastructural study defines more precisely the convoluted aspect but does not at present allow a distinction between the two groups.

References

Jul 15, 1978·Lancet·J H Baumer, M G Mott
Sep 1, 1976·Blut·D HuhnS Thierfelder
Oct 1, 1977·American Journal of Clinical Pathology·M PalutkeP M Tabaczka
Sep 1, 1978·Muscle & Nerve·F Behse, F Carlsen
Sep 1, 1977·The New England Journal of Medicine·J A DonlonR C Braylan
May 1, 1977·Clinical Immunology and Immunopathology·L MorettaP M Lydyard
Aug 1, 1978·Cancer·J C Brouet, M Seligmann
Sep 1, 1978·Annals of Internal Medicine·P J RosenR J Lukes
Aug 1, 1976·Cancer·B N NathwaniH Rappaport
Mar 15, 1976·International Journal of Cancer. Journal International Du Cancer·H SteinG Landbeck
May 1, 1975·Clinical Immunology and Immunopathology·M F GreavesT A Lister
Aug 1, 1967·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·P LorbacherW J Mitus
Jun 22, 1974·British Medical Journal·D CatovskyD A Galton
Oct 1, 1974·Cancer·R J Lukes, R D Collins
Nov 1, 1958·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M WACHSTEIN, G WOLF
Apr 1, 1964·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M HAYASHIW H FISHMAN
Jan 1, 1947·The Journal of Pathology and Bacteriology·H L SHEEHAN, G W STOREY

❮ Previous
Next ❯

Citations

Oct 1, 1985·Cancer·I MirchandaniM S Pak
Jul 1, 1991·Ultrastructural Pathology·C M PayneC M Spier
Jun 1, 1988·Australian and New Zealand Journal of Medicine·K F BradstockM Greenberg

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.