Lymphocyte adherence to myelinated tissue in multiple sclerosis

The Journal of Clinical Investigation
P Dore-DuffyB Rothman

Abstract

A small subpopulation of human peripheral blood T lymphocytes has the capacity to adhere selectively to myelinated sections of human and nonhuman brain tissue. Adherence of lymphocytes from patients with multiple sclerosis is significantly greater than adherence of control lymphocytes. Monocytes inhibit binding in controls. This function appears to be lost by multiple sclerosis monocytes.

References

Feb 1, 1979·Neurology·P Dore-DuffyH G Thompson
Jan 1, 1979·The Journal of Clinical Investigation·P Dore-Duffy, R B Zurier
Jun 24, 1976·The New England Journal of Medicine·N L LevyE C Hayes
Oct 1, 1972·The Journal of Clinical Investigation·J WybranH H Fudenberg

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Citations

Aug 24, 1999·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M ZaffaroniN Canal
Apr 15, 1983·Cellular Immunology·P Dore-Duffy, R B Zurier

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