PMID: 6169659Mar 15, 1981Paper

Lymphocyte-dependent antibodies to antigen 3.1, a cell-surface antigen expressed by a subgroup of human melanomas

International Journal of Cancer. Journal International Du Cancer
I HellströmM Y Yeh

Abstract

Previous work from our laboratory has led to the isolation of a monoclonal IgG2a mouse antibody, 3.2, which is specific for an antigen, 3.1, that is strongest expressed by a group of human melanomas. We have no demonstrated that this antibody can mediate antibody-dependent cellular cytotoxicity (ADCC) to human melanoma cells expressing antigen 3., and that lymphocytes from human peripheral blood can be used as the source of K cells. A monoclonal IgG1 antibody, 3.1, to the same determinant of antigen 3.1 gave only weak and inconsistent ADCC.

References

Jun 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M Y YehK E Hellström
Jan 1, 1969·Advances in Immunology·P Perlmann, G Holm
Mar 15, 1972·International Journal of Cancer. Journal International Du Cancer·S PollackK Nelson
Jan 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·J P BrownK E Hellström
Feb 15, 1981·International Journal of Cancer. Journal International Du Cancer·R G WoodburyI Hellström
Apr 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·R G WoodburyK E Hellström

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Citations

Mar 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·I HellströmK E Hellström
Sep 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·I HellströmK E Hellström
Jan 1, 1993·Cancer Investigation·U Kummer, U D Staerz
Jan 1, 1983·Annals of the New York Academy of Sciences·K ImaiA Yachi
Jan 1, 1984·Medical Oncology and Tumor Pharmacotherapy·K E HellströmJ P Brown

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