PMID: 11909763Mar 23, 2002Paper

Lymphocyte DNA damage in elevator manufacturing workers in Guangzhou, China

Mutation Research
Tai Hing LamChao Qiang Jiang

Abstract

To study the effect of smoking, passive smoking, alcohol drinking, and occupational exposure to low level of benzene on DNA strand breaks in elevator manufacturing workers in Guangzhou, China. Three hundred and fifty-nine workers (252 men and 107 women) of a modern elevator manufacturing factory, 205 were from production departments and 154 from managerial department. Information on the workers' health conditions, smoking, passive smoking, alcohol consumption and occupational exposure history was collected by personal interview. Lymphocyte DNA damage was measured by the Comet assay. None of the women smoked and 20.6% of the men were daily smokers. In non-smokers, the prevalence of passive smoking at work was 25% for men and 11.2% for women, and at home, 37.8 and 48.6%, respectively. Smoking significantly increased tail moment (P<0.001). Daily smokers had the largest tail moment (geometric mean, 95% CI) (0.93 microm (0.81-0.94)), followed by occasional smokers (0.76 microm (0.59-0.95)), ex-smokers (0.70 microm (0.58-0.85)), and never smokers (0.56 microm (0.53-0.60)). Tail moment increased significantly with daily tobacco consumption (cigarettes per day) (r=0.26, P<0.001) after adjusting for age, gender, occupational exposure, p...Continue Reading

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Citations

Jul 10, 2010·International Archives of Occupational and Environmental Health·Vellingiri BalachandarChinnakulandai Venkatesan
Mar 25, 2006·Occupational and Environmental Medicine·H TovalinE Rojas
Sep 24, 2009·Mutation Research·Kátia Regina Carvalho de AssisDaisy Maria Favero Salvadori
Jun 7, 2005·Chemico-biological Interactions·Panida NavasumritMathuros Ruchirawat
Jul 4, 2006·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Blanca LaffonJosefina Méndez
Sep 19, 2008·Environmental and Molecular Mutagenesis·Alok K PandeyAlok Dhawan
Dec 2, 2004·Mutation Research·David M DeMarini
Aug 5, 2008·Cell Biology International·Vanina Dahlström HeuserJosé Arthur Bogo Chies
Dec 2, 2004·Mutation Research·Kirsti Husgafvel-Pursiainen
Oct 23, 2003·American Journal of Industrial Medicine·Ana Bogadi-SareRajka Turk
Nov 11, 2005·Mutagenesis·Heike HoffmannGünter Speit
Oct 11, 2017·Mutagenesis·Malgorzata M DobrzynskaKatarzyna Owczarska
Jan 1, 2008·Environmental Health Insights·Beatriz Pérez-CadahíaBlanca Laffon

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