PMID: 6966116Jan 1, 1980Paper

Lymphocyte subpopulations in neonates, young children and adults as detected by six cell surface markers

Acta paediatrica Scandinavica
F Gmelig-MeylingR E Ballieux

Abstract

In this study, six surface marker tests were performed on lymphocytes from normal individuals of three age groups: neonates, children from 0 to 2 years of age, and adults. Determined were the proportions of T cells binding sheep red blood cells, of B cells carrying surface immunoglobulins or binding mouse red blood cells, and of lymphocytes bearing receptors for IgM, for IgG or for complement. The T cell percentage appeared to increase with the age; the percentage of B cells was highest in the children's group, as determined by both marker tests. Neonates had a much lower proportion of IgM-receptor bearing cells than older individuals. The variation in the percentages of T cells and of IgM-receptor bearing cells in the young age groups was relatively large as compared to adults. The significance of these observations is discussed; they may be of value for the proper evaluation of results obtained in diagnostical tests on neonates and young children.

References

Jan 1, 1977·Clinical Immunology and Immunopathology·A Ben-ZwiM Schlesinger
Apr 1, 1977·Cellular Immunology·S WitemeyerR C Williams
Jan 1, 1976·Journal of Immunological Methods·F Gmelig-MeylingR E Ballieux
Mar 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·S GuptaF P Siegal
Jul 1, 1976·Acta paediatrica Scandinavica·J S ChristiansenN Bach-Mortensen
Jan 1, 1976·Scandinavian Journal of Immunology·F Gmelig-MeylingR E Ballieux
Jan 1, 1975·European Journal of Immunology·M FerrariniM L Durante
Aug 1, 1975·European Journal of Immunology·L MorettaM C Mingari
May 1, 1975·The American Journal of Medicine·E Diaz-JauanenR C Williams
Nov 1, 1975·Clinical Immunology and Immunopathology·J W ChiaoR A Good
Apr 1, 1974·European Journal of Immunology·G Brown, M F Greaves
Oct 19, 1974·Lancet·M A SmithC M Steel
Jan 1, 1974·Advances in Immunology·N L Warner
Jan 1, 1974·International Archives of Allergy and Applied Immunology·S S FrolandT E Michaelsen
Jan 1, 1973·International Archives of Allergy and Applied Immunology·T HallbergR R Coombs
Jan 1, 1974·Advances in Immunology·V Nussenzweig

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Citations

Nov 1, 1994·Indian Journal of Pediatrics·A KumarP N Singla
Jun 27, 1984·Clinica Chimica Acta; International Journal of Clinical Chemistry·R J KraaijenhagenG E Staal
Nov 1, 1979·International Journal of Dermatology·G F HendrickxJ W Stoop
May 1, 1983·Acta paediatrica Scandinavica·S A PedersenV Andersen
Mar 1, 1980·Acta paediatrica Scandinavica·F Gmelig-MeylingJ W Stoop
Dec 30, 2014·Orvosi hetilap·Péter HollóSarolta Kárpáti
Jan 1, 1982·Histopathology·S C Van der PutteJ A Van Unnik
May 1, 1982·Acta paediatrica Scandinavica·A Hallberg, P Malmström

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