PMID: 6969531Apr 1, 1980Paper

Lymphocyte subpopulations in peripheral blood from schizophrenic patients

Acta Psychiatrica Scandinavica
H NylandH Lunde

Abstract

Patients with acute and chronic schizophrenia were examined for T and Fc receptor-bearing lymphocytes in blood by means of rosette techniques. The patients had normal numbers of peripheral blood lymphocytes. The percentage of T lymphocytes in patients with acute schizophrenia was reduced (60 +/-2%) compared with controls (66 +/- 1%) and patients with chronic schizophrenia (67 +/- 3%). The total number of T lymphocytes was significantly decreased in patients with acute schizophrenia had slightly elevated numbers (1,778 +/- 200 cells/mm3, P less than 0.002). The percentage and total numbers of Fc receptor-bearing lymphocytes were normal in both patient groups. Both immune mechanisms and the neuroleptic drug treatment may be of importance for the observed decrease in T lymphocyte numbers in blood from patients with acute schizophrenia.

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Citations

Jan 1, 1983·Journal of Neural Transmission·L E DeLisiR J Wyatt
Jun 1, 1986·Journal of Autism and Developmental Disorders·R P WarrenA Foster
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Oct 17, 2021·Expert Review of Neurotherapeutics·Prerna ChauhanHarmanjit Singh

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