Lymphocyte-To-Monocyte Ratio as the Best Simple Predictor of Bacterial Infection in Patients with Liver Cirrhosis

International Journal of Environmental Research and Public Health
Damian PiotrowskiAnna Boroń-Kaczmarska

Abstract

Background and aim: The aim of this study was to assess the diagnostic performance of new morphology-related indices and Child-Turcotte-Pugh (CTP) and Model for End-Stage Liver Disease (MELD) scores during hospitalization in predicting the onset of bacterial infection in patients with liver cirrhosis. Material and methods: A total of 171 patients (56.9% males; median age 59 years; total number of hospitalizations 209) with liver cirrhosis were included in this observational study. The diagnosis of cirrhosis was made on the basis of clinical, biochemical, ultrasonic, histological, and endoscopic findings. The neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), modified aspartate aminotransferase-to-platelet ratio index (APRI), aspartate aminotransferase-to-alanine aminotransferase ratio (AAR), Fibrosis-4 index (FIB-4), platelet-to-lymphocyte ratio (PLR), neutrophil-to-monocyte ratio (NMR), and CTP and MELD scores were calculated for the cases of patients with cirrhosis. Results: Bacterial infection was diagnosed in 60 of the 209 (28.7%) hospitalizations of patients with cirrhosis. The most common infections were urinary tract infection (UTI), followed by pneumonia and sepsis. The more severe the liver failu...Continue Reading

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Citations

Aug 12, 2020·International Journal of Laboratory Hematology·Hongmei ZhangZhongxin Lu
Aug 31, 2020·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Gina GheorgheCamelia Cristina Diaconu
Dec 22, 2020·The American Journal of Emergency Medicine·Yin-Chou HsuI-Ting Tsai
Aug 5, 2021·Experimental and Therapeutic Medicine·Roxana-Emanuela PopoiagCarmen Fierbințeanu-Braticevici

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Methods Mentioned

BETA
X-ray
biopsy

Software Mentioned

R
STATISTICA

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