Lymphocytopenia and thrombocytopenia during treatment with risperidone or clozapine

Pharmacopsychiatry
H J AssionG Laux

Abstract

The atypical antipsychotic clozapine is associated with several well-known abnormalities of blood cell count, whereas only rare reports are associated with the neuroleptic risperidone. This report describes lymphocytopenia and thrombocytopenia under treatment with risperidone which continued after changing to clozapine without other clinically significant abnormal hematological parameters. Within one week after discontinuation of both neuroleptics abnormalities of blood cell count reversed to the initial values. Abnormalities of lymphocytes or thrombocytes are rare side-effects under treatment with risperidone or clozapine.

Citations

Jun 28, 2008·Journal of Child and Adolescent Psychopharmacology·Murat Coskun, Nahit Motavalli Mukaddes
Jun 12, 2004·BMJ : British Medical Journal·Mira Harrison-Woolrych, David W J Clark
Jun 12, 2014·International Journal of Clinical Pharmacy·Norah O AbanmySolafa Fatani
Jan 13, 2009·General Hospital Psychiatry·Jun'ichi Semba, Shunichi Okui
Jul 3, 2021·Indian Journal of Psychiatry·Sachin Kumar SaxenaSweta Ratna

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