PMID: 39565Oct 1, 1979

Lymphocytotoxic antibodies in systemic lupus erythematosus and clinically related diseases

Arthritis and Rheumatism
A L Schocket, P F Kohler

Abstract

Sera from patients with systemic lupus erythematosus (SLE) and clinically related diseases were examined for cold-reactive lymphocytotoxic antibodies (LCA). The incidence of LCA was significantly increased in SLE (93%), discoid lupus (50%), and "lupus-like" syndromes associated with congenital complement deficiencies (63%) as compared to normal controls (3%) and patients with drug-induced lupus (11%), mixed connective tissue disease (MCTD) (17%), and necrotizing vasculitis (19%). The diagnostic and pathogenetic implications of these differences are discussed.

References

Nov 12, 1977·Lancet
Jan 1, 1978·The American Journal of Medicine·W J Fessel
Oct 1, 1978·The Journal of Allergy and Clinical Immunology·R G GowerR M McIntosh
Feb 1, 1976·Annals of Internal Medicine·J R MendiusR C Williams
Jul 1, 1976·Arthritis and Rheumatism·I MalavéZ Layrisse
Jun 1, 1975·The Journal of Clinical Investigation·R J DeHoratius, R P Messner
Dec 7, 1975·The New England Journal of Medicine·S J KorsmeyerR G Strickland
May 1, 1973·The Journal of Clinical Investigation·S W HuangR Hong
Oct 1, 1970·The New England Journal of Medicine·P I TERASAKIE V Barnett
Mar 28, 1970·Nature·K K MittalW T Butler
Nov 1, 1970·Transplantation·M J KreislerP I TERASAKI
Dec 5, 1964·Nature·C H VANGRAAN, C H WYNDHAM
Dec 5, 1964·Nature·P I TERASAKI, J D MCCLELLAND

Citations

Feb 1, 1981·Medizinische Monatsschrift für Pharmazeuten·G Cohnen
Jan 10, 2002·Annals of the Rheumatic Diseases·G E Eroglu, P F Kohler
Sep 1, 1980·The Journal of Clinical Investigation·N J DollJ E Salvaggio
Sep 1, 1982·The British Journal of Dermatology·A L SchocketD A Norris
Jan 1, 1981·Scandinavian Journal of Immunology·J JonssonR Norberg
Dec 1, 1983·Arthritis and Rheumatism·E Diaz-Jouanen, D Alarcon-Segovia
Oct 1, 1991·Clinical and Experimental Immunology·V TanejaA N Malaviya

Related Concepts

Lymphocyte Immune Globulin, Anti-Thymocyte Globulin (Equine)
Hemolytic Complement
Microcytotoxicity Test
Lupus Erythematosus, Discoid
Lupus Erythematosus, Systemic
Mixed Connective Tissue Disease
Polyarteritis Nodosa

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