Lymphoepitelioma-like carcinoma of the skin: report of three cases

Journal of Cutaneous Pathology
Verónica LópezEsperanza Jordá


Primary cutaneous lymphoepithelioma-like carcinoma (LELC) is an extremely rare cutaneous neoplasm with histopathological features similar to those seen in the undifferentiated subtype of nasopharyngeal carcinoma. Microscopically, the tumor is well circumscribed and is composed of irregular nests of malignant epithelial cells in a background of reactive lymphoid cells including mature plasma cells. Its histogenesis remains unknown although an adnexal or epidermic origin has been proposed, and despite its poorly differentiated histology, the LELC prognosis is relatively good. We describe three new cases of this entity that support an epidermic origin.


Apr 1, 1991·Journal of Cutaneous Pathology·M R WickP H Cooper
Aug 1, 1995·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·S E DozierG J Hruza
May 1, 1995·Journal of the American Academy of Dermatology·P Robins, M I Perez
Mar 1, 1995·American Journal of Clinical Pathology·J C IezzoniL M Weiss
Dec 1, 1996·The American Journal of Dermatopathology·T W ShekL K Lam
Jun 15, 2005·Journal of Cutaneous Pathology·Loren E Clarke, Michael D Ioffreda

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