Abstract
The purpose of this study was to review the chest radiographic, CT, and MRI appearances of primary pulmonary lymphoepithelioma-like carcinoma (LELC). Primary pulmonary LELC is histopathologically identical to nasopharyngeal carcinoma. The radiographic, CT, and MRI features of primary pulmonary LELC are nonspecific, often resembling those of bronchogenic carcinoma. Primary pulmonary LELC usually presents as a poorly circumscribed, enhancing, peripheral solitary pulmonary nodule on CT; necrosis may be present and is considered a poor prognostic sign. MRI shows isointense to low-intensity signal on T1-weighted images and mildly increased signal on T2-weighted images; enhancement of abnormal tissue is typical. Most patients present with early-stage disease. Primary pulmonary LELC should be suspected in selected patients and requires differentiation from bronchogenic carcinoma and metastatic nasopharyngeal carcinoma.
References
Sep 1, 1991·Journal of Surgical Oncology·B MillerR Kowalski
Aug 1, 1989·The American Journal of Surgical Pathology·A E ButlerC Lombard
Dec 1, 1987·Journal of Surgical Oncology·L R BéginL Panasci
Nov 1, 1995·Human Pathology·M HigashiyamaK Mishima
Mar 1, 1995·Tumori·G Ferrara, O Nappi
Jul 1, 1993·The American Journal of Surgical Pathology·S PittalugaS L Loke
Nov 1, 1995·The Journal of Pathology·M P WongK H Fu
Aug 1, 1995·Cancer·J K ChanY F Poon
Nov 1, 1995·Pathology, Research and Practice·W WöckelA Morresi
Jan 1, 1997·Chest·L D CurcioL M Weiss
Jun 1, 1997·Chest·C F Mountain
Nov 14, 1997·The Annals of Thoracic Surgery·M W FrankD A Fullerton
Jul 11, 1998·Cancer·F F ChenI J Su
Sep 10, 1998·Cancer·A T ChanP J Johnson
Jan 22, 2000·Radiology·S J SwensenA L Weaver
Mar 8, 2000·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·A BarrosoB Parente
Aug 15, 2000·American Journal of Clinical Pathology·A J HanY S Zong
Nov 4, 2000·Respiratory Medicine·J C HoK W Tsang
Jun 8, 2001·American Journal of Clinical Pathology·A J HanM Xiong
Aug 25, 2001·Human Pathology·C Y CastroJ Y Ro
May 23, 2002·The American Journal of Surgical Pathology·Yih-Leong ChangYung-Chie Lee
Jun 25, 2002·Asian Cardiovascular & Thoracic Annals·Neerod Kumar JhaJohn Stubberfield
Feb 21, 2003·European Radiology·G C OoiK W T Tsang
Jun 27, 2003·Human Pathology·Patrizia MorbiniUmberto Magrini
Citations
Mar 16, 2012·General Thoracic and Cardiovascular Surgery·Satona TanakaHiroshi Date
May 23, 2012·World Journal of Surgical Oncology·Joelle F S Wong, Melissa C C Teo
May 17, 2014·AJNR. American Journal of Neuroradiology·X BanR Zhang
Sep 19, 2007·The British Journal of Radiology·Chung-Jen HuangHorng-Chyuan Lin
Nov 30, 2013·Case Reports in Pulmonology·Yuan-Chun HuangChiung-Ying Liao
Mar 8, 2013·European Journal of Radiology·Huali MaYing Liang
Mar 20, 2015·Oncology Letters·Yasha LiangFengming Luo
Aug 16, 2016·Respirology Case Reports·Ryoko OiHaruhiko Nakamura
Jun 14, 2012·Clinical Nuclear Medicine·Daniel H Y ShenChing-Yuan Chen
Feb 22, 2018·Medicine·Chao XieJing Huang
Sep 21, 2017·Oncology Letters·Lan LinBangwei Zeng
Mar 3, 2017·Nuclear Medicine and Molecular Imaging·Gul Ege AktasAli Sarıkaya
Feb 18, 2021·Medicine·Lin ZhouShao-Jin Zhang