Lymphoepithelioma-like carcinoma of the lung: radiologic features of an uncommon primary pulmonary neoplasm

AJR. American Journal of Roentgenology
Joseph M HoxworthMichael B Gotway

Abstract

The purpose of this study was to review the chest radiographic, CT, and MRI appearances of primary pulmonary lymphoepithelioma-like carcinoma (LELC). Primary pulmonary LELC is histopathologically identical to nasopharyngeal carcinoma. The radiographic, CT, and MRI features of primary pulmonary LELC are nonspecific, often resembling those of bronchogenic carcinoma. Primary pulmonary LELC usually presents as a poorly circumscribed, enhancing, peripheral solitary pulmonary nodule on CT; necrosis may be present and is considered a poor prognostic sign. MRI shows isointense to low-intensity signal on T1-weighted images and mildly increased signal on T2-weighted images; enhancement of abnormal tissue is typical. Most patients present with early-stage disease. Primary pulmonary LELC should be suspected in selected patients and requires differentiation from bronchogenic carcinoma and metastatic nasopharyngeal carcinoma.

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Citations

Mar 16, 2012·General Thoracic and Cardiovascular Surgery·Satona TanakaHiroshi Date
May 23, 2012·World Journal of Surgical Oncology·Joelle F S Wong, Melissa C C Teo
Sep 19, 2007·The British Journal of Radiology·Chung-Jen HuangHorng-Chyuan Lin
Nov 30, 2013·Case Reports in Pulmonology·Yuan-Chun HuangChiung-Ying Liao
Aug 16, 2016·Respirology Case Reports·Ryoko OiHaruhiko Nakamura
Mar 3, 2017·Nuclear Medicine and Molecular Imaging·Gul Ege AktasAli Sarıkaya

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