PMID: 7536761May 1, 1995Paper

Lymphoepithelioma-like carcinoma of the skin treated with Mohs micrographic surgery in combination with immune staining for cytokeratins

Journal of the American Academy of Dermatology
F JimenezH Kamino

Abstract

Lymphoepithelioma-like carcinoma of the skin (LLCS) is a rare cutaneous neoplasm that histologically resembles nasopharyngeal lymphoepithelioma. Conventional surgical excision carries a considerable rate of recurrence (three of 11 reported cases with such treatment, with one patient dying of metastatic disease). We report the first case of lymphoepithelioma-like carcinoma of the skin treated with Mohs micrographic surgery. Because of its tendency to occur on the face and its potential for recurrence after incomplete removal, this tumor is a good candidate for treatment with Mohs micrographic surgery. Immunohistochemical staining of frozen sections for cytokeratins may help to detect neoplastic cells that may be obscured by the dense lymphoplasmacytic infiltrate associated with this tumor.

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Citations

Jun 17, 2006·The American Journal of Dermatopathology·Gillian HallNiamh Leonard
Feb 4, 2006·The American Journal of Dermatopathology·Samy FennicheSlim Haouet
Dec 21, 2004·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Daniel A DavisC William Hanke
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Nov 20, 2009·Journal of Cutaneous Pathology·Verónica LópezEsperanza Jordá
Jun 15, 2005·Journal of Cutaneous Pathology·Loren E Clarke, Michael D Ioffreda
Jan 19, 2008·Journal of Cutaneous Pathology·Pamela LyleSigurd Togerson
Oct 19, 2010·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Preston Q WelchJunu Ojha
Feb 1, 1997·The Journal of Dermatology·T KoT Shirai
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Jan 9, 2008·International Journal of Immunopathology and Pharmacology·S CavalieriM Rotoli
Jul 23, 1998·Journal of the American Academy of Dermatology·D L ShrinerR F Wagner

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