Lymphoepithelioma-like carcinoma of the urinary bladder: A case report and review of systemic treatment options.

Urology Annals
Nicholas M PantelidesErik K Mayer

Abstract

Lymphoepithelioma-like carcinoma (LELC) of the urinary bladder is a rare variant, which can occur in a pure form or in conjunction with transitional cell carcinoma. Owing to the scarcity of reported cases, the optimum treatment is yet to be defined, although the benefits of chemotherapy are increasingly recognised. We present a case of a 64-year-old man with pure LELC, treated with trans-urethral resection of the bladder tumor (TURBT) and primary gemcitabine and platinum-based chemotherapy. He remained free of disease at six-month follow-up cystoscopy. The case adds to the growing evidence for the efficacy of chemotherapy, coupled with TUR, as part of a bladder-preserving treatment option for LELC.

References

Jun 1, 1991·The American Journal of Surgical Pathology·L R ZukerbergR H Young
May 1, 1994·The American Journal of Surgical Pathology·M B AminA G Ayala
Mar 10, 2007·Nature Clinical Practice. Urology·Erik K MayerMathias H Winkler

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Citations

Jun 22, 2013·Journal of Medical Case Reports·Gian Paolo SpinelliSilverio Tomao
Dec 17, 2014·Journal of Medical Case Reports·Imad ZiouziouAhmed Iben Attya Andaloussi
May 28, 2013·Case Reports in Urology·Kenichi MoriHiromitsu Mimata
Sep 13, 2017·Nature Reviews. Urology·Marco MoschiniShahrokh F Shariat

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