PMID: 699110May 1, 1978Paper

Lymphoepitheloid malignant lymphoma (Lennert)

Ceskoslovenská patologie
B Bednár

Abstract

A group of 22 lymfoepitheloid malignant lymphomas was singled out from a wider group by means of demonstating nuclear atypias in epitheloid cells. There were three roughly equal subgroups: the first corresponding to malignant lymphogranuloma, the second to different malignant lymphomas of the ono-Hodgkin type. At first, the third group could not be recognized as a malignant lymphoma other than according to different sorts of atypia of each of the epitheloid cells in granulomas.--The general behaviour of malignant lymphomas of the first two subgroups was in keeping with the properties of the respective basic tumour. The third subgroup was more independent. At each subsequent check-up, the epitheloid granulomatous component of the tumour was seen gradually disappearing. It appeared to a secondary feature in most cases. The cause of atypia in epitheloid cells remained unexplained. Nonetheless, these atypias are an important diagnostic facilitating the identification of a more independent form of lymphoepitheloid malignant lymphoma, the subsequent development of which mostly shows signs of a moderately pleiomorphnous malignant lymphoma, sometimes obviously belonging in the T series.

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