PMID: 1203860Dec 1, 1975Paper

Lymphographic demonstration of cyclic changes in lymph node size during Pel-Epstein fever

Cancer
G T ScanlonR Rudders

Abstract

Pel-Epstein fever cycles, consisting of 1-2 weeks of high fever separated by afebrile periods of the same duration, are classically characteristic of Hodgkin's disease. Clinical observation has determined that the lymph nodes enlarge during periods of fever and reduce in size as the fever subsides. To our knowledge, the waxing and waning of lymph nodes in tempo with the fever cycle in Hodgkin's disease have never before been documented by lymphography. The alterations we verified radiographically resemble cyclic swings in classic autoimmune diseases. Speculations are offered regarding the observed changes.

References

Oct 1, 1966·Radiology·R J Steckel, T P Cameron
Apr 18, 1974·The New England Journal of Medicine·S Hellman
May 1, 1974·Radiology·B R ParkerR A Castellino

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Citations

Mar 4, 2000·AJR. American Journal of Roentgenology·P WunderbaldingerA A Bankier
Sep 23, 2000·AJR. American Journal of Roentgenology·R Aviv, K McHugh
Jan 1, 1988·Scandinavian Journal of Gastroenterology. Supplement·L Påhlman, B Glimelius

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