Nov 1, 1977

Lymphoid cells as effectors of immunologic cytolysis

Hospital Practice
J C Cerottini


Two classes of cytotoxic lymphocytes are described. One is composed of cytotoxic T lymphocytes (CTL), which have antigen specificity derived from prior immunization. The lymphocytes of the other class--the K cells--derive their limited specificity from affinity for antibodies on the surface of the target cells. Together these two lymphocyte classes provide a broad-spectrum defense against unwanted foreign and mutant cells.

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Mentioned in this Paper

Antigenic Specificity
Transplantation Immunology
Natural Killer Cells
Antibody Fragments
Immunologic Tumoricidal Activities
Plasma Membrane

About this Paper

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