Lymphoproliferative lung disorders: a radiologic-pathologic overview. Part II: Neoplastic disorders

Seminars in Ultrasound, CT, and MR
Carlos S RestrepoMicheal N Koss

Abstract

Lymphoproliferative pulmonary neoplasms can occur as primary pulmonary lymphomas or because of secondary pulmonary involvement. Neoplastic disorders may be difficult to differentiate from reactive pulmonary lymphoproliferative disorders, and immunohistochemical evaluation is often required to differentiate the 2 types of lesions. Neoplastic lymphoproliferative disorders are monoclonal lesions. Most affected patients present with systemic complaints, and imaging findings typically include nodules, masses, and lymphadenopathy. Primary pulmonary lymphomas are rare and account for less than 4% of the lymphomas that arise in extranodal sites. Secondary pulmonary lymphomas can affect the lung via hematogenous dissemination or by secondary involvement from tumor in adjacent or contiguous sites. Neoplastic lymphoproliferative lesions also include leukemia and plasma cell neoplasms. Posttransplantation lymphoproliferative disorders constitute a special type of lymphoid proliferation occurring in the setting of the chronic immunosuppression required for solid organ and bone marrow transplantation.

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Citations

Jun 5, 2016·Seminars in Ultrasound, CT, and MR·Shameem AzizadCarlos S Restrepo
Oct 10, 2015·Advances in Anatomic Pathology·Sergio Piña-OviedoCesar A Moran
Jun 7, 2016·Radiologic Clinics of North America·Emily Heckendorn, Aaron Auerbach
Oct 5, 2019·La Radiologia medica·Diletta CozziVittorio Miele
Aug 24, 2017·The British Journal of Radiology·Domenico AlbanoFrancesco Bertagna
Jun 19, 2019·Scientific Reports·Wen DengJian-Qun Yu
Jan 28, 2021·Cancers·Francesca SanguedolceStefano Ascani

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