Lysozyme distribution in human lacrimal glands and other ocular adnexa

Archives of Ophthalmology
I G Rennie, M A Parsons

Abstract

In an immunohistochemical study of the human lacrimal glands and other orbital adnexa, lysozyme was found to be present in the major and accessory lacrimal glands but absent from meibomian glands and conjunctival epithelium. Almost all acinar and tubular cells in major and accessory lacrimal glands contain lysozyme, although occasional cells show diminished staining for lysozyme, probably because of secretion. Only one secretory lacrimal tubuloacinar cell type is demonstrable, although two types previously have been described. Lacrimal duct cells do not contain lysozyme. The findings of this study support the concept that the tubuloacinar cells of the main and accessory lacrimal glands are the sole source of the lysozyme secreted into tears.

Citations

Apr 1, 1985·Current Eye Research·H H Stolze, H J Sommer
May 29, 2016·Tissue & Cell·María VásquezCarolina Zanuzzi
Dec 3, 2009·Experimental Eye Research·Zhenjun ZhaoMark D P Willcox
Sep 17, 2010·Journal of Biomaterials Science. Polymer Edition·Wen-Yu SuFeng-Huei Lin
Apr 18, 2017·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Almudena CrookeJesus Pintor

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