Machine learning and modeling: Data, validation, communication challenges

Medical Physics
Issam El NaqaRandall Ten Haken

Abstract

With the era of big data, the utilization of machine learning algorithms in radiation oncology is rapidly growing with applications including: treatment response modeling, treatment planning, contouring, organ segmentation, image-guidance, motion tracking, quality assurance, and more. Despite this interest, practical clinical implementation of machine learning as part of the day-to-day clinical operations is still lagging. The aim of this white paper is to further promote progress in this new field of machine learning in radiation oncology by highlighting its untapped advantages and potentials for clinical advancement, while also presenting current challenges and open questions for future research. The targeted audience of this paper includes newcomers as well as practitioners in the field of medical physics/radiation oncology. The paper also provides general recommendations to avoid common pitfalls when applying these powerful data analytic tools to medical physics and radiation oncology problems and suggests some guidelines for transparent and informative reporting of machine learning results.

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Citations

Jan 23, 2020·The British Journal of Radiology·Issam El NaqaRandall K Ten Haken
Apr 22, 2020·Journal of Dental Research·F SchwendickeJ Krois
May 18, 2020·Medical Physics·Yi LuoGilmer Valdes
Nov 14, 2019·International Journal of Molecular Sciences·Robersy SanchezSally A Mackenzie
Dec 20, 2020·Australian Dental Journal·F Pethani
Jan 15, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Christian HarrerJan J Wilkens
Oct 17, 2020·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Joanna KazmierskaAlberto Traverso
Mar 16, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Yoganand BalagurunathanIssam El Naqa
Apr 3, 2021·Annual Review of Biomedical Engineering·Habib Zaidi, Issam El Naqa
Nov 26, 2018·Oncology·Huan-Hsin TsengIssam El Naqa

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