Machine Learning for Precision Health Economics and Outcomes Research (P-HEOR): Conceptual Review of Applications and Next Steps

Journal of Health Economics and Outcomes Research
Yixi ChenXin Gao

Abstract

Precision health economics and outcomes research (P-HEOR) integrates economic and clinical value assessment by explicitly discovering distinct clinical and health care utilization phenotypes among patients. Through a conceptualized example, the objective of this review is to highlight the capabilities and limitations of machine learning (ML) applications to P-HEOR and to contextualize the potential opportunities and challenges for the wide adoption of ML for health economics. We outline a P-HEOR conceptual framework extending the ML methodology to comparatively assess the economic value of treatment regimens. Latest methodology developments on bias and confounding control in ML applications to precision medicine are also summarized.

References

Sep 18, 1996·JAMA : the Journal of the American Medical Association·A F ConnorsW A Knaus
Feb 4, 2012·Statistics in Medicine·Mousumi BanerjeeAnne-Michelle Noone
May 28, 2015·The New England Journal of Medicine·J Larry Jameson, Dan L Longo
Mar 25, 2016·Nature Reviews. Cardiology·John S RumsfeldThomas M Maddox
May 25, 2016·Scientific Data·Alistair E W JohnsonRoger G Mark
May 27, 2016·The International Journal of Biostatistics·Heidi SeiboldTorsten Hothorn
Oct 22, 2016·Critical Care Medicine·Ilona Willempje Maria VerburgNicolette Fransisca de Keizer
Apr 6, 2017·PharmacoEconomics·Daisuke GotoC Daniel Mullins
Jun 21, 2017·Statistical Methods in Medical Research·Demissie AlemayehuMarianthi Markatou
Jan 4, 2018·Annals of Internal Medicine·Vaibhav KumarDavid M Kent
Jan 5, 2018·Statistical Methods in Medical Research·Heidi SeiboldTorsten Hothorn
Jan 5, 2018·Statistical Methods in Medical Research·Jiaqi LiNandita Mitra
Jan 20, 2018·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Tara A LavellePeter J Neumann
Mar 14, 2018·JAMA : the Journal of the American Medical Association·Andrew L Beam, Isaac S Kohane
Jul 14, 2018·PharmacoEconomics·James Love-KohMatthew Taylor
Apr 4, 2019·Applied Health Economics and Health Policy·Patrick FahrSarah Wordsworth
Jun 5, 2019·Statistics in Medicine·Jon Arni Steingrimsson, Jiabei Yang
Sep 27, 2019·Journal of Managed Care & Specialty Pharmacy·Louis P Garrison, Adrian Towse
Mar 7, 2020·Forum for Health Economics & Policy·David L VeenstraScott D Ramsey

❮ Previous
Next ❯

Software Mentioned

R
HEOR
SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Mental Health Policy and Economics
The Milbank Memorial Fund Quarterly. Health and Society
H E Klarman
Duodecim; lääketieteellinen aikakauskirja
A Liikkanen
Canadian Medical Association Journal
K L Meloff
© 2021 Meta ULC. All rights reserved