Macondo crude oil from the Deepwater Horizon oil spill disrupts specific developmental processes during zebrafish embryogenesis.

BMC Biology
T Yvanka de SoysaMichael J F Barresi

Abstract

The Deepwater Horizon disaster was the largest marine oil spill in history, and total vertical exposure of oil to the water column suggests it could impact an enormous diversity of ecosystems. The most vulnerable organisms are those encountering these pollutants during their early life stages. Water-soluble components of crude oil and specific polycyclic aromatic hydrocarbons have been shown to cause defects in cardiovascular and craniofacial development in a variety of teleost species, but the developmental origins of these defects have yet to be determined. We have adopted zebrafish, Danio rerio, as a model to test whether water accumulated fractions (WAF) of the Deepwater Horizon oil could impact specific embryonic developmental processes. While not a native species to the Gulf waters, the developmental biology of zebrafish has been well characterized and makes it a powerful model system to reveal the cellular and molecular mechanisms behind Macondo crude toxicity. WAF of Macondo crude oil sampled during the oil spill was used to treat zebrafish throughout embryonic and larval development. Our results indicate that the Macondo crude oil causes a variety of significant defects in zebrafish embryogenesis, but these defects hav...Continue Reading

References

May 1, 1981·The Journal of Comparative Neurology·C B KimmelR J Kimmel
Nov 7, 1995·Proceedings of the National Academy of Sciences of the United States of America·H W DetrichL I Zon
Nov 1, 1995·Nature Medicine·B M WeinsteinM C Fishman
Feb 13, 1999·Cell·D L Vaux, S J Korsmeyer
Oct 12, 2000·Ecotoxicology and Environmental Safety·C J PfeifferL Gray
Nov 7, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·H L StickneyS H Devoto
Feb 13, 2001·Developmental Dynamics : an Official Publication of the American Association of Anatomists·R LuoP D Henion
Aug 29, 2001·Journal of Anatomy·C B KimmelR J Keynes
Sep 25, 2003·Human Molecular Genetics·David I Bassett, Peter D Currie
Jan 7, 2004·Journal of Physiology, Paris·Edna BrusteinPierre Drapeau
Aug 10, 2004·Clinical and Experimental Pharmacology & Physiology·David Bassett, Peter D Currie
Sep 29, 2004·Neurotoxicology and Teratology·Mark J ReimersRobert L Tanguay
Feb 11, 2005·Toxicological Sciences : an Official Journal of the Society of Toxicology·Adrian J HillRichard E Peterson
Apr 29, 2005·Nature·Barbara A BlockThomas D Williams
Feb 14, 2006·Journal of Neuroscience Methods·Michael H GriderH David Shine
Feb 14, 2006·Journal of Neurobiology·Gerald B Downes, Michael Granato
May 9, 2006·Marine Pollution Bulletin·Shahunthala D RamachandranJennifer A Dixon
Nov 2, 2006·Advances in Experimental Medicine and Biology·Martín L Basch, Marianne Bronner-Fraser
Nov 2, 2006·Advances in Experimental Medicine and Biology·Robert D Knight, Thomas F Schilling
Apr 18, 2007·Proceedings of the National Academy of Sciences of the United States of America·Thomas E HallPeter D Currie
Apr 19, 2007·Nature Reviews. Genetics·Graham J Lieschke, Peter D Currie
Apr 24, 2007·Marine Pollution Bulletin·Jennifer B CulbertsonRachel VanderKruik
May 4, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Harold A Burgess, Michael Granato
May 9, 2007·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Scott A Holley
Jun 30, 2007·Birth Defects Research. Part C, Embryo Today : Reviews·Emily T Shifley, Susan E Cole
Jul 24, 2007·Mechanisms of Development·Olivier Cinquin
Oct 31, 2007·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Hae-Chul ParkBruce Appel
Mar 29, 2008·Methods in Molecular Biology·Robert L Tanguay, Mark J Reimers
May 16, 2008·Aquatic Toxicology·Mark G CarlsJohn P Incardona
Feb 28, 2009·The International Journal of Developmental Biology·Moisés MalloMarta Carapuço
Jun 27, 2009·Annual Review of Neuroscience·Arnold Kriegstein, Arturo Alvarez-Buylla

❮ Previous
Next ❯

Citations

Oct 2, 2013·Aquatic Toxicology·John P IncardonaNathaniel L Scholz
Dec 10, 2013·The Journal of Clinical Investigation·Ksenia N TonyushkinaRolf O Karlstrom
Apr 8, 2014·Proceedings of the National Academy of Sciences of the United States of America·John P IncardonaNathaniel L Scholz
Aug 12, 2014·Ecotoxicology and Environmental Safety·Sandy RaimondoMace G Barron
Mar 13, 2014·Expert Opinion on Drug Metabolism & Toxicology·Demetrio Raldúa, Benjamin Piña
Mar 5, 2015·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Nobuo SuzukiKazuichi Hayakawa
Apr 22, 2014·Aquatic Toxicology·Sarah P CohenChristopher S Lassiter
May 14, 2016·Environmental Science & Technology·Danielle A PhilibertKeith B Tierney
Jun 16, 2016·Marine Pollution Bulletin·Jonny BeyerTracy K Collier
Oct 21, 2016·Environmental Toxicology and Chemistry·Nancy J Brown-PetersonRobert J Griffitt
Mar 27, 2018·Toxicology and Industrial Health·Benjamin S WalkerChristopher S Lassiter
Jan 18, 2018·Veterinary Clinical Pathology·Kendal E HarrRyan A Takeshita
Apr 18, 2018·Environmental Toxicology and Chemistry·Maria L RodgersMaria S Sepúlveda
May 8, 2020·Journal of Toxicology and Environmental Health. Part a·Mónica Améndola-PimentaRossanna Rodríguez-Canul
May 30, 2020·Environmental Science and Pollution Research International·Muliari MuliariMohammad Mahmudur Rahman
Apr 25, 2013·Journal of Basic and Clinical Physiology and Pharmacology·Onyenmechi Johnson AfonneOrish Ebere Orisakwe
Feb 26, 2020·International Journal of Environmental Research and Public Health·Masato Honda, Nobuo Suzuki
Dec 4, 2020·Environmental Science and Pollution Research International·Sarah JohannThomas-Benjamin Seiler
Feb 1, 2021·The Science of the Total Environment·Prescilla PerrichonSonnich Meier
Apr 18, 2021·Scientific Reports·Morgan Lizabeth BenderJasmine Nahrgang
Jul 10, 2019·Marine Environmental Research·Bjørn Henrik HansenElin Kjørsvik
May 26, 2021·Environmental Science & Technology·Alexis J KhursigaraAndrew J Esbaugh
Jun 9, 2021·Journal of Fish Diseases·Chong WangQingli Zhang
Nov 17, 2021·Environmental Science and Pollution Research International·Simrith E Córdova-de la CruzCarlos Alfonso Alvarez-González

❮ Previous
Next ❯

Methods Mentioned

BETA
transgenic

Software Mentioned

Volocity
Excel
Axiovision
Adobe Photoshop
AxioImager

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis