PMID: 19128745Jan 9, 2009Paper

Macroamylasaemia in paediatrics

Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)
A Torrent VernettaD Infante Pina

Abstract

Macroamylasaemia should be considered in any patient with high plasma amylase, no clinical signs and negative additional investigations for pancreatic or parotid diseases. It is characterised by an increase in serum amylase due to circulating high molecular mass macrocomplexes, most often formed due the binding of the amylase to an immunoglobulin. With a normal renal function, a hyperamylasaemia without an increase in urine amylase suggests the diagnosis, and is confirmed by identifying the macromolecular components. It is an uncommon entity in paediatrics. It has been described as a casual finding associated to abdominal pain and to celiac disease. We report two paediatric cases of macroamylasaemia, and a review of the tests needed for its diagnosis. The better understanding of this biochemical anomaly allows us to differentiate it from other situations associated to hyperamylasaemia, in order to avoid additional invasive explorations and unnecessary treatments.

References

Jan 1, 1992·Journal of Pediatric Gastroenterology and Nutrition·M D'AvanzoF Iafusco
Nov 2, 1967·The New England Journal of Medicine·J E BerkR L Searcy
Apr 24, 2001·The American Journal of Gastroenterology·A RabsztynK Horvath
Aug 2, 2001·Gastroenterología y hepatología·I I MontalvoJ I Arenas
Oct 11, 2001·Journal of Pediatric Gastroenterology and Nutrition·A J DeprettereV Van Hoof
Jul 2, 2002·The Journal of Pediatrics·James P Keating, Mark E Lowe
May 13, 2003·Scandinavian Journal of Gastroenterology·J F BermejoE Fernandez-Cruz
Oct 15, 2005·BMJ : British Medical Journal·Rajeev SrivastavaMichael J Murphy
Jan 26, 2006·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·I DaireB Le Luyer
Apr 20, 2007·Digestive Diseases and Sciences·Zhanju LiuFuai Tang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Deutsche medizinische Wochenschrift
W RothenbergerK H Weber
Archives of Disease in Childhood
C CatassiP L Giorgi
European Journal of Clinical Investigation
H KöhlerH J Horstmann
© 2021 Meta ULC. All rights reserved