Macrolide and clindamycin resistance in Staphylococcus aureus isolates and antibiotic use in a Veterans Affairs Medical Center

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Rohit ModakVirginia L Kan

Abstract

A retrospective analysis of 13,946 Staphylococcus aureus isolates revealed a stable incidence of isolates that were resistant to both clindamycin and erythromycin, but a significantly increasing incidence of isolates that were susceptible to clindamycin and resistant to erythromycin during 1991-1995, 1996-2000, and 2001-2005. The use of macrolides and clindamycin also increased during 1996-2005. The incidence of S. aureus isolates with inducible clindamycin resistance increased steadily and significantly during the period from August 2004 through December 2005.

References

Mar 5, 1998·JAMA : the Journal of the American Medical Association·B C HeroldR S Daum
Jun 25, 2003·Current Opinion in Infectious Diseases·John F Marcinak, Arthur L Frank
Jun 22, 2005·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·O K AzapU Gagir

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Citations

Apr 30, 2010·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Riza AdaletiSemiha Tasdemir

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