PMID: 3321409Dec 1, 1987Paper

Macrophages in T and B cell compartments and other tissue macrophages recognized by monoclonal antibody MOMA-2. An immunohistochemical study

Scandinavian Journal of Immunology
G KraalM Janse

Abstract

A new monoclonal antibody, MOMA-2, is described, which recognizes monocytes and macrophages in the mouse. The antibody reacts with the majority of mononuclear phagocytes in various tissues as determined by immunohistochemistry. It differs from other macrophage markers that have been described by the strong reaction with macrophages in the lymphoid organs such as the tingible body macrophages and macrophages in T cell-dependent areas. The antibody recognizes predominantly a cytoplasmic component, although a membrane component can also be demonstrated. Isolated Langerhans' cells, interdigitating cells and dendritic cells, members of the mononuclear phagocyte system that are involved in antigen presenting, stain weakly with the antibody. Because of the intense staining the antibody is very useful for defining tissue macrophages by immunohistochemistry.

References

Apr 1, 1979·European Journal of Immunology·T SpringerC Milstein
Apr 1, 1976·The Journal of Investigative Dermatology·I SilberbergS A Rosenthal
Mar 1, 1985·The Journal of Experimental Medicine·G Schuler, R M Steinman
Jan 1, 1980·Immunological Reviews·R M Steinman, M C Nussenzweig
Jul 1, 1982·The Journal of Experimental Medicine·W E KlinkertW E Bowers
Apr 1, 1982·Immunobiology·E C HoefsmitE W Kamperdijk
Oct 1, 1981·European Journal of Immunology·J M Austyn, S Gordon

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Citations

Feb 1, 1997·Muscle & Nerve·A Pimorady-EsfahaniP G McMenamin
Feb 19, 2000·Journal of Biomedical Materials Research·I M KhouwM J van Luyn
Apr 13, 1999·Journal of Cellular Physiology·J M OwensT J Chambers
Sep 28, 2000·Journal of Biomedical Materials Research·I M KhouwM J van Luyn
Nov 28, 2000·Journal of Biomedical Materials Research·I M KhouwM J van Luyn
Mar 29, 2002·International Journal of Cancer. Journal International Du Cancer·Lill-Tove R BusundRolf Seljelid
Mar 1, 1992·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J A KerbyT J Chambers
Jun 1, 1994·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S NiidaH Kodama
Apr 27, 2013·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Jihyun LeeStephen Desiderio
Aug 26, 1993·Journal of Immunological Methods·J JanousekF Gervais
Sep 14, 1994·Journal of Immunological Methods·P J LeenenW van Ewijk
Jun 14, 1996·Journal of Immunological Methods·T L ten HagenI A Bakker-Woudenberg
Dec 1, 1992·Journal of Pharmacological and Toxicological Methods·N van Rooijen, A Poppema
Oct 15, 2003·Burns : Journal of the International Society for Burn Injuries·Hilda ShalloElizabeth J Kovacs
Dec 9, 1998·Clinical and Experimental Immunology·L A DielemanE P Van Rees
Oct 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·D G SkalnikS H Orkin
Jun 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·T J ChambersM D Noble
Oct 15, 1996·Proceedings of the National Academy of Sciences of the United States of America·A GalG N Wogan
May 27, 2010·The Journal of Biological Chemistry·Liza J Raggatt, Nicola C Partridge
Nov 1, 1995·The Journal of Experimental Medicine·S KahnM Kahn
Sep 1, 1996·The Journal of Experimental Medicine·C C BleulT A Springer
Oct 23, 2002·Molecular and Cellular Biology·Evelyne SchallerKlaus Pfeffer
Jun 19, 2010·Arteriosclerosis, Thrombosis, and Vascular Biology·Vladimir R BabaevJames M May
Aug 3, 2004·The Journal of Clinical Investigation·Can ShiDaniel I Simon
Aug 4, 2006·The Journal of Clinical Investigation·Honglin WangKarin Scharffetter-Kochanek
Feb 7, 2013·BMC Immunology·Changqi WangDavid Ch Harris
Jul 14, 1998·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·W Chen, Y P Li
Apr 14, 2007·Radiology·Jonathan B KruskalS Nahum Goldberg

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