Macroscopic 2D networks self-assembled from nanometer-sized protein/DNA complexes

Nano Letters
Maximino ManzaneraPaul D Barker

Abstract

We demonstrate the self-assembly of DNA and DNA binding proteins into two-dimensional networks that are then addressable by sending a second protein to a specific recognition site on the DNA network. These networks cover centimeters in area but can be addressed with nanometer precision. This hierarchical self-assembly of specific DNA protein complexes will be the basis for complex positioning of single molecules in two and three dimensions.

Citations

Dec 8, 2007·Bioconjugate Chemistry·Wei Jie Qin, Lin Yue Lanry Yung

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