Macroscopic and microscopic measurement of myocardial infarct size. A comparison

Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie
N BankaP L Wahi


Infarct size measured by microscopic method is consistently larger than that measured macroscopically, indicating that certain areas of infarction are missed when observed macroscopically. Existence of a good correlation between the two methods, however, suggests that macroscopic estimation of infarct size would be enough for initial screening of the interventions designed for salvation of ischemic myocardium, as it is an easy method. An additional advantage of this method is that it can be utilized to measure infarct size as early as 72 h after production of infarction. Comparison of weight and volume method of macroscopic estimation of infarct size has shown that they do not give significantly different results. Weight method being less cumbersome and less time-consuming, may be adopted for initial screening of cardioprotective agents.


Jun 4, 2013·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·GuiLan SunYi Feng
Sep 25, 2008·Interactive Cardiovascular and Thoracic Surgery·Takeshi ShimamotoMasashi Komeda
Apr 1, 2014·Cardiovascular Toxicology·Jindan CaiY James Kang
Dec 4, 2012·Journal of Pharmacological and Toxicological Methods·Edgars LiepinshMaija Dambrova
Mar 4, 2008·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Gitika KhannaAmteshwar S Jaggi


Nov 1, 1975·British Heart Journal·R RobertsB E Sobel
Mar 31, 1976·The American Journal of Cardiology·B E SobelK B Larson
Nov 1, 1973·Archives of Surgery·W S PierceJ A Waldhausen
Jul 25, 1974·The New England Journal of Medicine·B L HolmanR Gorlin
Oct 1, 1972·Circulation·B E SobelR D Yoder
Jul 15, 1971·The New England Journal of Medicine·D L PageC A Sanders
Nov 1, 1970·British Heart Journal·C HarnarayanD B Brewer
Jul 1, 1970·British Heart Journal·C HanarayanB L Pentecost

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