Macrosomia, top of the iceberg: the charm of underlying factors

Pediatrics International : Official Journal of the Japan Pediatric Society
M M Donma

Abstract

Macrosomia is associated with childhood obesity. Gestational diabetes mellitus (GDM) is a risk factor for macrosomia. The aim of this large-scale investigation was to determine the incidence, risk factors, characteristic features, and perinatal outcome of macrosomic infants. This prospective study was carried out on 6385 newborns. Demographic data included maternal age, paternal age, type of delivery, sex, parity and gestational age at delivery. Anthropometric measurements were recorded. ABO/Rh typing was performed and GDM was diagnosed. Out of 6385 term deliveries, 477 infants (7.47%) were macrosomic. Incidence of GDM was 0.6% and 4.8% in the control group and in macrosomic births, respectively. Incidence of GDM(+) cases was 4% among macrosomic infants weighing 4000-4500 g. GDM(+) cases were densely populated (11%) in macrosomic infants weighing ≥ 4500 g (P ≤ 0.05). Male/female ratio was significantly higher in macrosomic infants weighing ≥ 4500 g than those weighing 4000-4500 g (P ≤ 0.05). High parental age was the risk factor for GDM. Blood group A was the most frequently observed type among mothers with macrosomic infants, however, blood group O was dominant in cases with GDM. In multivariate logistic regression analysis, t...Continue Reading

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Citations

Sep 5, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·M O'Keeffe, M-P St-Onge
Jun 25, 2013·Journal of Biosocial Science·Georgia Verropoulou, Stuart Basten
Aug 1, 2012·Journal of Pregnancy·Sandeep RahaAlison C Holloway
Jun 9, 2012·Journal of Perinatology : Official Journal of the California Perinatal Association·C Phaloprakarn, S Tangjitgamol
Jul 26, 2014·The International Journal of Eating Disorders·Anu RaevuoriJaana Suvisaari

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