Macular choroidal thickness in non-arteritic ischemic optic neuropathy

Archivos de la Sociedad Española de Oftalmología
Ignacio García-BasterraJosé Manuel García-Campos

Abstract

To analyse macular choroidal thickness (MCT) in non-arteritic ischaemic optic neuropathy (NAION). An analysis was made on 22 patients diagnosed with NAION (22 eyes) and 42 healthy controls (42 eyes) using enhanced-depth imaging of spectral-domain optical coherence tomography. A horizontal raster scan centred on the fovea was obtained per eye 3 months after the onset of NAION. Three measurements of MCT were obtained from the posterior edge of the retinal pigment epithelium to the choroid-sclera junction at 500μm intervals. Statistical analysis was used to compare the mean MCT and to correlate MCT with other ocular and systemic parameters. Except for refractive error (P=.01), there were no statistically significant differences between both groups in axial length (P=.53), age (P=.88) and other epidemiological and ocular parameters. Mean MCT in NAION eyes and control group was 236.21±63.29μm and 269.13±52.28, respectively. Mean MCT was significantly thinner in NAION eyes than in healthy eyes (P=.03). Thinner MCT, adjusted for refractive error, was associated with the diagnosis of NAION (P=.04). Eyes affected by NAION showed significantly thinner MCT compared with healthy control eyes after adjusting for refractive error.

References

Feb 15, 1994·American Journal of Ophthalmology·A C Arnold, R S Hepler
Oct 3, 1999·Experimental Eye Research·J W Kiel
Nov 30, 2000·Experimental Eye Research·J W Kiel
Sep 8, 2004·Ophthalmology·Nathalie J Collignon-RobeJoseph F Rizzo
Nov 18, 2005·Experimental Eye Research·Elke Lütjen-Drecoll
Jul 27, 2007·Investigative Ophthalmology & Visual Science·Elzbieta PolskaLeopold Schmetterer
Jul 22, 2008·American Journal of Ophthalmology·Richard F SpaideMaria C Pozonni
Dec 10, 2008·Progress in Retinal and Eye Research·Sohan Singh Hayreh
Dec 15, 2011·Investigative Ophthalmology & Visual Science·Colin S TanSriniVas R Sadda
Sep 27, 2012·Ophthalmology·Wen Bin WeiQi Sheng You
Nov 10, 2012·Investigative Ophthalmology & Visual Science·Karun S AroraHarry A Quigley
Jun 15, 2013·The British Journal of Ophthalmology·Ignacio Flores-MorenoJosé M Ruiz-Moreno

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