Abstract
To investigate the association between macular features on spectral-domain optical coherence tomography (SD-OCT) and visual acuity (VA) in Coats' disease. Thirty-nine eyes (39 patients) with SD-OCT from January 1, 2008 to December 31, 2016 were reviewed for SD-OCT features. Central subfield (CSF) SD-OCT findings were analyzed relative to VA (logarithm of the minimum angle of resolution) at baseline and final visit (when follow-up ≥ 6 months) and across visits. Mean VA ± standard deviation at baseline (37 eyes) was 0.92 ± 0.82. SD-OCT features associated with worse VA included, for treatment-naïve eyes (n = 21), outer retinal atrophy (ORA) (1.18 ± 0.34 with versus 0.20 ± 0.30 without, P = 0.005), subretinal fluid (SRF) (1.80 ± 0.63 vs. 0.63 ± 0.50, P = 0.008), bright hyperreflectivities (1.23 ± 0.68 vs. 0.52 ± 0.53, P = 0.02), thicker foveal subretinal space (r2 = 0.32, P = 0.01), and CSF (r2 = 0.39, P = 0.007); and for previously treated eyes (n = 16), a compact hyperreflective structure (1.60 ± 0.88 vs. 0.56 ± 0.64, P = 0.02) and ORA (1.34 ± 0.86 vs. 0.30 ± 0.44, P = 0.01). At final follow-up (n = 22), mean VA was 0.81 ± 0.83. Eyes with final VA <20/200 (n = 6, vs. >20/60, n = 11) more commonly had a compact hyperreflective st...Continue Reading
References
Jun 10, 1998·Controlled Clinical Trials
May 5, 2001·American Journal of Ophthalmology·J A ShieldsJ Cater
Mar 9, 2002·Retina·Jerry A Shields, Carol L Shields
Oct 20, 2004·Retina·Tomohiro OtaniShoji Kishi
Dec 22, 2004·Journal of Pediatric Ophthalmology and Strabismus·Carol L ShieldsJerry A Shields
Mar 3, 2007·The Journal of Clinical Investigation·Martin Friedlander
Apr 23, 2008·International Ophthalmology Clinics·Michael P Rubin, Shizuo Mukai
Jan 15, 2010·Investigative Ophthalmology & Visual Science·Ramiro S MaldonadoCynthia A Toth
Apr 27, 2010·Retina·J Michael JumperEmmett T Cunningham
May 23, 2012·Case Reports in Ophthalmology·Rivka KessnerMeira Neudorfer
Jul 26, 2012·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Christopher R HenryTimothy G Murray
Jan 21, 2014·Journal of Biomedical Optics·Francisco A FolgarCynthia A Toth
Aug 30, 2014·Retina·Eric J Sigler, Jorge I Calzada
Feb 3, 2015·American Journal of Ophthalmology·Robert B BhisitkulKang Zhang
Apr 1, 2015·Ophthalmology·Martina Suzani, Anthony T Moore
May 16, 2015·Retina·Abdullah A Al-QahtaniNicola G Ghazi
May 29, 2015·Journal of Biomedical Optics·Francisco A FolgarCynthia A Toth
Jul 21, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Nora W MuakkassaCaroline R Baumal
Dec 29, 2016·Retina·Alejandra L DaruichFrancis L Munier
Apr 6, 2017·Journal of Ophthalmology·Wojciech HautzBeata Kocyła-Karczmarewicz
May 4, 2017·Ophthalmology·Sally S OngPrithvi Mruthyunjaya
Jun 15, 2017·Retina·Ana R SantosJose G Cunha-Vaz
Sep 7, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Alessandro RabioloFrancesco Bandello
Citations
Nov 27, 2018·JAMA Ophthalmology·Sally S OngCynthia A Toth
Nov 27, 2018·JAMA Ophthalmology·Irena Tsui, Stacy L Pineles
Jul 18, 2020·BMJ Case Reports·Subhakar ReddyPadmaja Kumari Rani
Feb 23, 2020·Therapeutic Advances in Ophthalmology·Bradley S Gundlach, Irena Tsui
Mar 22, 2019·International Ophthalmology·Xinyue YangGuanfang Su
Oct 18, 2020·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Sophie CaiLejla Vajzovic