Macular Structures, Optical Components, and Visual Acuity in Preschool Children after Intravitreal Bevacizumab or Laser Treatment

American Journal of Ophthalmology
Yung-Sung LeeWei-Chi Wu

Abstract

To investigate the macular structures, optical components, and visual acuity in preschool-aged children with a history of type I retinopathy of prematurity who underwent either intravitreal bevacizumab (IVB), laser, or a combination of treatments. Comparative interventional case series. Setting: A referred medical center in Taiwan. Eighty eyes from 42 patients (33 IVB-treated eyes from 17 children, 24 laser-treated eyes from 13 children, and 23 laser + IVB-treated eyes from 12 children). Spectral-domain optical coherence tomography. The retinal thickness in the foveal area and the associated morphologic changes in foveal depression. Compared with the laser-treated and laser + IVB-treated eyes, the IVB-treated eyes had less myopia and deeper anterior chamber depths but presented similar axial lengths and corneal curvatures (P = .001, P = .002, P = .95, and P = .16, respectively). The IVB-treated eyes had significantly thinner foveal, parafoveal, and perifoveal retinal thicknesses (P < .01 for all) and a higher incidence of foveal depression than the laser- or laser + IVB-treated eyes. The macular and subfoveal choroidal thicknesses did not differ among the groups (P = .21 and P = .63, respectively). Moreover, compared with the e...Continue Reading

Citations

Apr 19, 2019·Ophthalmic Surgery, Lasers & Imaging Retina·Mary Elizabeth Hartnett, Cynthia Ann Toth
Nov 26, 2019·Retina·Eugene Yu-Chuan KangWei-Chi Wu
Feb 24, 2019·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·Jost B Jonas, Songhomitra Panda-Jonas
Jul 8, 2020·Survey of Ophthalmology·Efthymia ProusaliAsimina Mataftsi
Mar 22, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Tomoya MurakamiTetsuro Oshika

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