PMID: 11910229Mar 23, 2002Paper

Mafenide acetate allergy presenting as recurrent chondritis

Annals of Plastic Surgery
Evan J PickusRichard A Korentager

Abstract

Acute chondritis has a strong predilection for recurrence. Mafenide acetate has been implicated in causing reactions that mimic this condition; however, these hypersensitivity reactions lack fever, fluctuance, and pain. The authors report a case of mafenide acetate allergy presenting as recurrent chondritis in a patient who had previously been treated successfully for this condition. In this patient, the allergic response resolved within 3 days after cessation of mafenide acetate. If unappreciated, it may have led to unnecessary operative intervention. Therefore, auricular edema and erythema, without fever, fluctuance, and pain, must be recognized by surgeons as a possible mafenide acetate allergy and must be considered in the differential diagnosis for patients who present with recurrent acute suppurative chondritis.

References

Jan 1, 1979·Scandinavian Journal of Plastic and Reconstructive Surgery·S P PeggM Laundy
Mar 1, 1988·The Journal of Burn Care & Rehabilitation·A W PerryM R Madden
Aug 1, 1987·Plastic and Reconstructive Surgery·S S Kroll, F J Gerow
Oct 1, 1971·Plastic and Reconstructive Surgery·R N OllsteinL Pelle
Aug 1, 1968·Plastic and Reconstructive Surgery·J A DowlingJ A Moncrief

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Citations

Dec 13, 2006·American Journal of Otolaryngology·Joon Kyoo LeeSang Chul Lim
Apr 14, 2005·The Annals of Otology, Rhinology, and Laryngology·Ron EliasharJean-Yves Sichel

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