Magnaporthe oryzae-Secreted Protein MSP1 Induces Cell Death and Elicits Defense Responses in Rice

Molecular Plant-microbe Interactions : MPMI
Yiming WangKyu Young Kang

Abstract

The Magnaporthe oryzae snodprot1 homolog (MSP1), secreted by M. oryzae, is a cerato-platanin family protein. msp1-knockout mutants have reduced virulence on barley leaves, indicating that MSP1 is required for the pathogenicity of rice blast fungus. To investigate the functional roles of MSP1 and its downstream signaling in rice, recombinant MSP1 was produced in Escherichia coli and was assayed for its functionality. Application of MSP1 triggered cell death and elicited defense responses in rice. MSP1 also induced H2O2 production and autophagic cell death in both suspension-cultured cells and rice leaves. One or more protein kinases triggered cell death, jasmonic acid and abscisic acid enhanced cell death, while salicylic acid suppressed it. We demonstrated that the secretion of MSP1 into the apoplast is a prerequisite for triggering cell death and activating defense-related gene expression. Furthermore, pretreatment of rice with a sublethal MSP1 concentration potentiated resistance to the pathogen. Taken together, our results showed that MSP1 induces a high degree of cell death in plants, which might be essential for its virulence. Moreover, rice can recognize MSP1, resulting in the induction of pathogen-associated molecular pa...Continue Reading

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Citations

Jun 9, 2016·International Journal of Molecular Sciences·Simone LutiLuigia Pazzagli
Jun 2, 2017·Virulence·Thabiso E Motaung, Toi J Tsilo
Aug 28, 2019·International Journal of Molecular Sciences·Ravi GuptaSun Tae Kim
Jun 4, 2019·Applied Microbiology and Biotechnology·Haizhen NieHongmei Zeng
Nov 19, 2019·Frontiers in Plant Science·Qingfeng MengSun Tae Kim
Dec 7, 2018·Open Biology·Jie Tang, Diane C Bassham
Jul 8, 2020·Biomolecules·Riyazuddin RiyazuddinRavi Gupta
Nov 5, 2020·Current Genetics·Amrita PradhanGopaljee Jha
Feb 6, 2018·Trends in Microbiology·Jessie Fernandez, Kim Orth
Feb 6, 2017·Microbiology Spectrum·Gunther DoehlemannAmir Sharon
Aug 17, 2021·Microbiological Research·Catalina Landeta-SalgadoMaría Elena Lienqueo
Oct 9, 2021·Plant Molecular Biology·Guihua DuanJing Yang

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