PMID: 15232810Jul 3, 2004Paper

Magnesium in addition to sotalol does not influence the incidence of postoperative atrial tachyarrhythmias after coronary artery bypass surgery

Journal of Cardiothoracic and Vascular Anesthesia
Hans GeertmanMichelle van Rooyen-Butijn

Abstract

Postoperative atrial tachyarrhythmias (POATs) after coronary artery bypass grafting (CABG) are reported in 11% to 40% of patients. Several etiologic factors are mentioned. Prophylactic intervention with sotalol is reported to reduce the incidence of POAT. The authors studied the effect of magnesium chloride (MgCl2) in addition to sotalol in the prevention of POAT. Prospective, randomized, double-blinded, placebo-controlled trial. Single center. After institutional approval and written informed consent, patients undergoing CABG with use of cardiopulmonary bypass were included in a prospective, randomized, placebo-controlled double-blind study. In 74 patients, intravenous MgCl2, 50 mmol/24 hours, was continuously administered after the induction of anesthesia during 36 hours; 73 patients received placebo. In both groups, sotalol orally was started 16 to 24 hours after CABG. The incidence and duration of in-hospital POAT were evaluated. A total of 147 patients could be evaluated: in the magnesium-treated group (n = 74), 25 patients developed POAT (34%) and in the placebo group (n = 73) 19 patients (26%) (p = 0.36). There was no statistically significant difference in duration of POAT between the groups. In the magnesium-treated gr...Continue Reading

References

Nov 4, 1992·JAMA : the Journal of the American Medical Association·M R EnglandB Chernow
Jun 1, 1991·Journal of Cardiothoracic and Vascular Anesthesia·L S AglioB Chernow
Apr 1, 1994·Journal of Cardiothoracic and Vascular Anesthesia·P A CasthelyM Kelly
Feb 1, 1993·The Thoracic and Cardiovascular Surgeon·U NyströmK Rådegran
Jan 1, 1997·Scandinavian Cardiovascular Journal : SCJ·B M JensenN A Klitgård
Feb 2, 2000·The Annals of Thoracic Surgery·A J SolomonN M Katz
Apr 11, 2000·The Thoracic and Cardiovascular Surgeon·G SpezialeB Marino

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Citations

Jul 28, 2006·Current Medical Research and Opinion·Eduard ShantsilaGregory Y H Lip
Nov 13, 2012·The Annals of Thoracic Surgery·Richard C CookKarin H Humphries
May 9, 2012·Journal of Cardiothoracic and Vascular Anesthesia·Gildasio S De OliveiraRobert J McCarthy
Jun 5, 2013·Pacing and Clinical Electrophysiology : PACE·Harsha V GangaJeffrey Kluger
Dec 6, 2005·Journal of Cardiothoracic and Vascular Anesthesia·Alberto ZangrilloGiuseppe Crescenzi
Jan 24, 2009·Wiener medizinische Wochenschrift·Rita Lenk, Rudolf Likar
Nov 2, 2005·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Daniel E HillemanStephanie Maciejewski
Sep 11, 2019·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Yousef RezaeiSaeid Hosseini

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