Magnesium ions and barium coating of colonic mucosa: is it a simple question of viscosity?

European Radiology
G CittadiniG Cittadini

Abstract

The aim of the present study was to verify whether magnesium-induced increase of barium coating of the colonic mucosa is specifically due to the increase of barium suspension viscosity. One hundred sixty-one patients scheduled for double-contrast barium enema (DCBE) were randomised in one group of 23 patients (control group, CG), and three groups of 23 pairs (G1, G2 and G3), i.e. 138 patients. The DCBE was performed with standard technique using a barium suspension with dynamic viscosity of 280 cPs (CG), or with viscosity increased to 320 cPs (G1), 2500 cPs (G2) or 3200 cPs (G3), by extemporaneous addition of MgSO4 1, 2 or 3 g in one member of the pair, Na2SO4 1, 4.2 or 8 g in the other one. Three radiologists evaluated on an ordinal scale mucosal coating and free fluid. In all magnesium subgroups barium coating was better than in CG (p < 0.008), the highest value being obtained in G2. No difference was observed as regards free fluid. Inside paired groups, mucosal coating was more effective in magnesium than in sodium members (p < 0.0002). Viscosity of barium suspension being equal inside each group, this effect must be attributed to magnesium-specific interactions with additives of the barium suspension inducing events other t...Continue Reading

Citations

Aug 22, 2009·AJR. American Journal of Roentgenology·Giovanni MaconiGabriele Bianchi Porro
Dec 21, 2006·Academic Radiology·Stacy D O'Connor, Ronald M Summers
Feb 25, 2017·Journal of Controlled Release : Official Journal of the Controlled Release Society·Mark Martin JensenHamidreza Ghandehari

Related Concepts

Micropaque Oral
Taenia Coli
Radiographic contrast media
Administration of Enema
Structure of Intestinal Gland
Magnesium
Diagnostic Radiologic Examination
Sodium
Suspensions
Viscosity

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