Abstract
Magnesium may be beneficial in the control of ventricular ectopy and supraventricular tachyarrhythmias after coronary artery bypass graft (CABG) surgery, but it is not known whether a high-dose magnesium regimen is superior to a regimen keeping the patient normomagnesemic. A prospective randomized and double-blind clinical comparison was performed in 81 elective CABG patients in order to assess the effects of two different magnesium infusion regimens on electrolyte balance and postoperative arrhythmias. Forty-one patients (high-dose group, H) received 4.2 +/- 0.7 g (mean +/- SD), of magnesium sulfate before cardiopulmonary bypass, followed by an infusion of 11.9 +/- 2.8 g of magnesium chloride until the first postoperative (PO) morning, and a further 5.5 +/- 1.0 g until the second PO morning. Forty patients (low-dose group, L) received magnesium sulfate only after bypass to a total of 2.9 +/- 0.5 g at the first, and 1.4 +/- 0.1 g at the second PO morning. A blood cardioplegia technique was used in both groups, including bolus doses of magnesium chloride to a total of 2.4 +/- 0.6 g and 2.3 +/- 0.6 g to H and L patients, respectively. Continuous Holter tape-recording was used for 12 to 15 hours preoperatively, and for 48 hours po...Continue Reading
References
Jun 27, 1992·Lancet·K L WoodsY Haider
Nov 4, 1992·JAMA : the Journal of the American Medical Association·M R EnglandB Chernow
Jul 1, 1992·Southern Medical Journal·A H YurvatiP P Koro
Dec 14, 1991·BMJ : British Medical Journal·K K TeoR Peto
Jun 1, 1991·Journal of Cardiothoracic and Vascular Anesthesia·D C Finlayson
Jun 1, 1991·Journal of Cardiothoracic and Vascular Anesthesia·L S AglioB Chernow
Sep 11, 1991·The Annals of Thoracic Surgery·W J FanningW S Stoney
Oct 1, 1991·Journal of Cardiothoracic and Vascular Anesthesia·K D Knopes, B R Hecker
Dec 15, 1990·The American Journal of Cardiology·L H CrosbyJ A Burkholder
Jun 1, 1990·Canadian Journal of Physiology and Pharmacology·A Bril, L Rochette
Aug 1, 1986·International Journal of Cardiology·L F SmithD B Barnett
Apr 1, 1987·Hypertension·J L NadlerR K Rude
Oct 1, 1989·Journal of Cardiothoracic Anesthesia·I M SchwiegerD C Finlayson
Feb 1, 1986·Lancet·H S RasmussenS Balslev
Jun 1, 1988·British Journal of Anaesthesia·M N HarrisC Aps
Jul 1, 1987·British Journal of Pharmacology·B T Altura, B M Altura
Apr 1, 1987·Archives of Internal Medicine·A S AbrahamU Eylath
Jan 1, 1985·The American Journal of Cardiology·B R HeckerR S Crampton
Apr 1, 1985·The Annals of Thoracic Surgery·R DavisonL Michaelis
Dec 1, 1985·The Journal of Surgical Research·Y YanoJ C Alexander
Mar 1, 1972·Thorax·M P HoldenG H Wooler
Oct 1, 1984·The Annals of Thoracic Surgery·J W HammonH W Bender
Sep 1, 1993·The Annals of Thoracic Surgery·J L Cox
Sep 1, 1993·The Annals of Thoracic Surgery·L L CreswellJ L Cox
Feb 1, 1993·European Heart Journal·H ParikkaM S Nieminen
Citations
Oct 31, 2006·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Joel DunningUNKNOWN EACTS Audit and Guidelines Committee
Feb 2, 2000·The Annals of Thoracic Surgery·C W Hogue, M L Hyder
Apr 16, 1998·Journal of Electrocardiology·J E Tamis, J S Steinberg
Aug 10, 1999·Journal of the American College of Cardiology·T GuarnieriD R Lowry
Jul 17, 1998·Anesthesiology·M N Gomez
Apr 16, 2005·Heart·S MillerS J Connolly
Dec 2, 2010·Journal of Cardiothoracic Surgery·Ioanna KoniariDimitrios Dougenis
Sep 28, 2002·Anesthesia and Analgesia·Nicholas J WilkesRobin Walesby
Dec 3, 2014·Cardiology Clinics·Mrinal YadavaThomas Christopher Crawford
May 9, 2012·Journal of Cardiothoracic and Vascular Anesthesia·Gildasio S De OliveiraRobert J McCarthy
Mar 13, 2016·Heart Failure Clinics·Mrinal YadavaThomas Christopher Crawford
Jul 1, 1999·American Heart Journal·J D RedleH I Frumin
Sep 1, 2004·The American Journal of Medicine·Toshiya ShigaRyo Ogawa
Aug 12, 2004·Pharmacotherapy·Alexandria A Piotrowski, James S Kalus
Oct 29, 2000·Journal of Cardiothoracic and Vascular Anesthesia·A D MaslowR G Johnson
Feb 13, 2003·The Journal of Thoracic and Cardiovascular Surgery·Mehmet KaplanMahmut Murat Demirtas
Sep 3, 1998·Chest·D Brathwaite, C Weissman
Apr 25, 2007·Scandinavian Cardiovascular Journal : SCJ·Hakala TapioHartikainen Juha
Apr 13, 2004·American Heart Journal·Johann AuerUNKNOWN Study of Prevention of Postoperative Atrial Fibrillation
Jul 23, 2003·The Journal of International Medical Research·Y BeşoğulR Aslan
Feb 19, 2004·British Journal of Anaesthesia·P-G ChassotD R Spahn
Jun 1, 1997·Anesthesiology·J L Atlee
Sep 11, 2019·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Yousef RezaeiSaeid Hosseini
Jun 30, 2018·BMC Cardiovascular Disorders·Shirvan SalaminiaMorteza Motedayen
Sep 24, 2009·Circulation·Richard C CookMay K Lee