Magnesium with micro-arc oxidation coating and polymeric membrane: an in vitro study on microenvironment

Journal of Materials Science. Materials in Medicine
Honglong LiGuoxin Ni

Abstract

Numerous modification methods have been reported to enhance the corrosion resistance of magnesium with positive results. However, little attention has been paid on their impact on micro-environment, particularly the ion concentration and local pH value. In this study, two different coatings were prepared on magnesium, one with porous micro-arc oxidation (MAO) coating alone, and the other with additional polymer polyhydroxybutyrate (PHB) membrane using spinning technique. Their in vitro corrosional and biological behaviors were investigated and compared. Both coatings were found to reduce the degradation rate of magnesium, but an additionally deposited PHB membrane was superior to MAO-coated magnesium since it could produce a micro-environment with preferable local pH value and ion concentration for osteoblast proliferation. Our study suggests that micro-environment should be another critical issue in evaluation of a modification method for orthopaedic implants.

References

Sep 5, 2002·Journal of Biomedical Materials Research·H ZreiqatM Shakibaei
Oct 26, 2005·Biomaterials·Mark P StaigerGeorge Dias
Jul 4, 2007·Journal of Materials Science. Materials in Medicine·Alexis PietakMark P Staiger
Jun 25, 2008·Journal of Nanoscience and Nanotechnology·Ming-Xing ZhangPatrick M Kelly
Sep 6, 2008·Journal of Cellular Biochemistry·Jonathan D Kaunitz, Dean T Yamaguchi
Feb 23, 2010·Acta Biomaterialia·Frank Witte
Feb 12, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Yuhui ShenJiang Chang
Mar 30, 2011·Annals of Biomedical Engineering·Jingxin YangIn Seop Lee
Jun 2, 2011·Journal of Materials Science. Materials in Medicine·Meiqing GuoXinhua Xu

❮ Previous
Next ❯

Citations

Sep 29, 2020·International Journal of Nanomedicine·Xiaodong LiLing Zhang
Feb 27, 2021·Journal of Biomaterials Applications·Quan LiangHanyan Zou
Nov 5, 2019·Acta Pharmaceutica : a Quarterly Journal of Croatian Pharmaceutical Society and Slovenian Pharmaceutical Society, Dealing with All Branches of Pharmacy and Allied Sciences·Barbara Dariš, Željko Knez

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Materials Science. Materials in Medicine
Junjie GanWeirong Li
Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas
W H MaY Z Zhang
© 2021 Meta ULC. All rights reserved