Magnetic nanoformulations for prostate cancer

Drug Discovery Today
Pallabita ChowdhuryMurali M Yallapu

Abstract

Magnetic nanoparticles (MNPs) play a vital role for improved imaging applications. Recently, a number of studies demonstrate MNPs can be applied for targeted delivery, sustained release of therapeutics, and hyperthermia. Based on stable particle size and shape, biocompatibility, and inherent contrast enhancement characteristics, MNPs have been encouraged for pre-clinical studies and human use. As a theranostic platform development, MNPs need to balance both delivery and imaging aspects. Thus, this review provides significant insight and advances in the theranostic role of MNPs through the documentation of unique magnetic nanoparticles used in prostate cancer, their interaction with prostate cancer cells, in vivo fate, targeting, and biodistribution. Specific and custom-made applications of various novel nanoformulations in prostate cancer are discussed.

References

Nov 1, 2016·Molecular Pharmaceutics·Zheyu ShenXiaoyuan Chen

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Citations

Mar 26, 2019·Chemical Communications : Chem Comm·Olga V KuznetsovaAndrei R Timerbaev
Mar 1, 2019·International Journal of Molecular Sciences·Monira SarkisKamil Rahme
Feb 9, 2021·Bioactive Materials·Benilde AdrianoMurali M Yallapu
Oct 7, 2019·Drug Discovery Today·Edouard Alphandéry

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