Magnetic resonance diffusion tensor imaging of the optic nerves to guide treatment of pediatric suprasellar tumors

Pediatric Neurosurgery
Michael B SalmelaChristopher G Filippi

Abstract

As a preoperative planning tool, conventional magnetic resonance (MR) imaging may have limited value in differentiating tumors from white matter tracts. MR diffusion tensor imaging (MRDTI) has become a useful tool for evaluating white matter tracts in relation to surrounding structures and has been used in surgical planning for brain tumors involving white matter. We investigated the use of DTI of the optic nerves in surgical planning for pediatric suprasellar tumors. We present findings in 10 pediatric control patients and 2 cases of pediatric suprasellar tumors in which a routine 6-direction DTI of the brain was performed at 3 T. Postprocessing permitted the study of the diffusion tensor parameters, as well as the tractography, of the optic nerves. The control patients demonstrated the optimization of the technique and permitted the quantitation of fractional anisotropy and apparent diffusion coefficient values. The tumor cases demonstrated the utility of optic nerve DTI to differentiate between optic nerves and suprasellar/chiasmatic brain tumors. A routine 6-direction DTI of the pediatric brain at 3 T permits a detailed DTI study of the optic nerves. Optic nerve tractography can be used to aid in the evaluation and treatmen...Continue Reading

Citations

Dec 10, 2009·Pediatric Radiology·Michael B SalmelaChristopher G Filippi
Apr 27, 2013·AJR. American Journal of Roentgenology·Michael J PlazaGaurav Saigal
Mar 1, 2013·CNS Oncology·Iris FriedEric Bouffet
Jun 1, 2016·Endocrinology and Metabolism Clinics of North America·Jad M Bou-Ayache, Bradley N Delman
Sep 10, 2016·Radiology Research and Practice·Yan ZhangXuelin Zhang
Jun 26, 2010·Journal of Magnetic Resonance Imaging : JMRI·Joshua P NickersonChristopher G Filippi
May 3, 2019·Pediatric Radiology·Pun Janthanimi, Netsiri Dumrongpisutikul
Jul 17, 2018·Neurosurgery·Timothée JacquessonFrancois Cotton

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