Magnetic resonance diffusion tensor imaging of cervical microstructure in normal early and late pregnancy in vivo

American Journal of Obstetrics and Gynecology
Wenxu QiYong Wang

Abstract

Cervical remodeling is an important aspect of birth timing. Before cervical ripening, the collagen fibers are arranged in a closely interweaved network, but during ripening, the fibers become disorganized and the cervix becomes more hydrated. To quantitatively measure cervical remodeling, we need a noninvasive method to monitor changes in cervical collagen fiber organization and hydration in vivo. To use diffusion tensor imaging to image and quantify the spatial and temporal differences in cervical microstructure between normal early and late pregnancies. After institutional review board approval and consent, a group of healthy women in early pregnancy (22 patients at 12-14 weeks' gestation) and a group in late pregnancy (27 patients at 36-38 weeks' gestation) underwent magnetic resonance imaging on a Siemens MAGNETOM Vida 3 Tesla unit. Diffusion tensor imaging of the cervix in the axial plane was performed with a two-dimensional single-shot echo planar imaging diffusion-weighted sequence. In early and late pregnancy groups, the differences of the diffusion tensor imaging measures were compared between the subglandular zone and the outer stroma regions of the cervix. In addition, the diffusion tensor imaging measures were compa...Continue Reading

References

Apr 1, 1992·British Journal of Obstetrics and Gynaecology·K S Oláh, H Gee
Mar 1, 1983·Clinical Obstetrics and Gynecology·D N Danforth
Jul 1, 1996·European Journal of Obstetrics, Gynecology, and Reproductive Biology·L K Petersen, N Uldbjerg
Dec 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·C Pierpaoli, P J Basser
Aug 20, 2004·Glycobiology·Kelly J StraachMala S Mahendroo
Oct 6, 2005·American Journal of Obstetrics and Gynecology·Michael HouseRafeeque A Bhadelia
Jun 1, 2006·Journal of Magnetic Resonance Imaging : JMRI·Deborah Levine
Jan 6, 2007·Seminars in Reproductive Medicine·R Ann WordKelley Carrick
Jul 31, 2007·Reproduction : the Official Journal of the Society for the Study of Fertility·Charles P ReadMala S Mahendroo
Mar 21, 2008·Matrix Biology : Journal of the International Society for Matrix Biology·Monika RuscheinskyMala Mahendroo
Feb 23, 2010·Trends in Endocrinology and Metabolism : TEM·Brenda TimmonsMala Mahendroo
Oct 5, 2010·NMR in Biomedicine·Dmitriy A Yablonskiy, Alexander L Sukstanskii
Dec 16, 2011·Brain : a Journal of Neurology·Yong WangSheng-Kwei Song
Jun 22, 2012·American Journal of Obstetrics and Gynecology·Helen FeltovichVincenzo Berghella
Aug 23, 2012·Biochemical and Biophysical Research Communications·S GhazanfariC V C Bouten
Mar 15, 2013·Frontiers in Neuroscience·José M SoaresNuno Sousa
May 7, 2014·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Yves PatenaudeUNKNOWN Society of Obstetricians and Gynaecologists of Canada
Apr 7, 2015·Journal of Biomechanics·Kristin M MyersMichael House
Oct 16, 2016·Neoplasia : an International Journal for Oncology Research·Samata KakkadZaver M Bhujwalla
Mar 5, 2017·Journal of Perinatal Medicine·Vera OturinaRalf Schmitz
May 17, 2017·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·N BañosM Palacio
Nov 22, 2017·Biology of Reproduction·Shanmugasundaram NallasamyMala Mahendroo
Dec 12, 2017·BJOG : an International Journal of Obstetrics and Gynaecology·J P NottNab Simpson
Feb 8, 2018·American Journal of Obstetrics and Gynecology·Christine M O'BrienAnita Mahadevan-Jansen
May 2, 2018·Reproduction : the Official Journal of the Society for the Study of Fertility·Jia HaoEve Donnelly

❮ Previous
Next ❯

Citations

Mar 3, 2021·Reproductive Sciences·Kenichiro MotomuraNardhy Gomez-Lopez

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists
Philipp HendrixR Shane Tubbs
Pediatric Radiology
Mickaël LairPierre-Hugues Vivier
Diagnostic and Interventional Radiology : Official Journal of the Turkish Society of Radiology
Bengi GürsesNevzat Gürmen
NMR in Biomedicine
Matt G Hall, Thomas R Barrick
© 2021 Meta ULC. All rights reserved