Magnetic resonance elastography of the plantar fat pads: Preliminary study in diabetic patients and asymptomatic volunteers

Journal of Computer Assisted Tomography
Yvonne CheungJohn Weaver

Abstract

To test the feasibility of applying the magnetic resonance elastography (MRE) technique to map the elastic modulus of the plantar fat pads in diabetic and nondiabetic subjects. A prototype MRE imaging apparatus was used to produce quantitative maps of the heel fat pad in a pilot study of 12 volunteers and 4 patients with diabetes with neuropathy. Anatomic images corresponding to MRE maps allowed precise selection of regions of interest in the fat. Magnetic resonance elastograms of the heel fat pads were successfully created; mean measurements in the volunteers and the diabetic patients were 4.85 and 5.26 kPa, respectively. It is feasible to perform MRE on the plantar fat pads and to produce elasticity maps. The trend toward stiffer fat pads, as demonstrated in patients with diabetes, suggests that the fat pads were qualitatively different. Magnetic resonance elastography offers great potential to investigate the mechanical properties of soft tissues in vivo noninvasively.

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Citations

Mar 3, 2010·Neurosurgical Review·Antonio Di IevaRiccardo Rodriguez Y Baena
Feb 18, 2011·Annals of Biomedical Engineering·Shruti Pai, William R Ledoux
Jun 15, 2011·Physics in Medicine and Biology·Huifang WangKeith D Paulsen
Nov 15, 2011·Journal of Biomechanics·Shruti Pai, William R Ledoux
Nov 28, 2016·Magnetic Resonance Imaging Clinics of North America·Ching-Di Chang, Jim S Wu
Jul 29, 2010·Journal of Diabetes Science and Technology·James S Wrobel, Bijan Najafi
Nov 5, 2011·Foot & Ankle International·Yak-Nam WangWilliam R Ledoux
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Apr 14, 2018·Biomedical Engineering Online·Dan L Bader, Peter R Worsley
Apr 30, 2021·Journal of Foot and Ankle Research·Benedictine Yen Chen KhorRuth Barn
Apr 29, 2008·Magnetic Resonance Imaging Clinics of North America·J Matthew RussellLaura W Bancroft
Sep 26, 2009·Clinics in Podiatric Medicine and Surgery·Thomas M Rocchio

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