Magnetic Resonance-Guided Focused Ultrasound: A Brief Review With Emphasis on the Treatment of Extra-abdominal Desmoid Tumors

Ultrasound Quarterly
Michael O GriffinSean M Tutton

Abstract

Magnetic resonance-guided focused ultrasound (MRgFUS) utilizes high-intensity focused ultrasound to noninvasively, thermally ablate lesions within the body while sparing the intervening tissues. Magnetic resonance imaging provides treatment planning and guidance, and real-time magnetic resonance thermometry provides continuous monitoring during therapy. Magnetic resonance-guided focused ultrasound is ideally suited for the treatment of extra-abdominal desmoid fibromatosis due to its noninvasiveness, lack of ionizing radiation, low morbidity, and good safety profile. Conventional treatments for these benign tumors, including surgery, radiation, and chemotherapy, can carry significant morbidity. Magnetic resonance-guided focused ultrasound provides a safe and effective alternative treatment in this often-young and otherwise healthy patient population. While there is considerable experience with MRgFUS for treatment of uterine fibroids, painful bone lesions, and essential tremor, there are few reports in the literature of its use for treatment of benign or malignant soft tissue tumors. This article reviews the principles and biologic effects of high-intensity focused ultrasound, provides an overview of the MRgFUS treatment system ...Continue Reading

References

Jan 1, 1991·Ultrasound in Medicine & Biology·K Hynynen
Dec 1, 1972·The Journal of the Acoustical Society of America·J A Rooney
Jun 1, 1984·International Journal of Radiation Oncology, Biology, Physics·S A Sapareto, W C Dewey
Jul 1, 1960·IRE Transactions on Medical Electronics·W J FRY, F J FRY
Jul 17, 2004·Annual Review of Biomedical Engineering·Diane Dalecki
Jun 21, 2007·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Gail Ter Haar, Constantin Coussios
Jan 26, 2008·Journal of Magnetic Resonance Imaging : JMRI·Viola Rieke, Kim Butts Pauly
Oct 4, 2008·The American Journal of Pathology·Alexander J F LazarDina Lev
Nov 20, 1942·The Journal of General Physiology·J G LynnA E Miller
Jul 30, 2011·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Yang WangJie Tang
Mar 12, 2013·Cardiovascular and Interventional Radiology·Alessandro NapoliCarlo Catalano
Oct 15, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Elizabeth RamsayRajiv Chopra
Dec 17, 2014·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C ColomboS Bonvalot
Mar 12, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·N EastleyR Ashford
Aug 6, 2016·Physics in Medicine and Biology·Kullervo Hynynen, Ryan M Jones
Aug 25, 2016·The New England Journal of Medicine·W Jeffrey EliasJin W Chang
Nov 25, 2016·Journal of Therapeutic Ultrasound·Eugene OzhinskyViola Rieke
Jun 6, 2017·Mayo Clinic Proceedings·Keith M Skubitz
Jun 6, 2017·Journal of Magnetic Resonance Imaging : JMRI·Kagayaki Kuroda

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Citations

Dec 8, 2020·Journal of the National Comprehensive Cancer Network : JNCCN·Margaret von MehrenGiby V George
Sep 5, 2020·Surgical Oncology Clinics of North America·Nathan W MeskoDaniel P Raymond
Aug 24, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Rong ZhangWen-Zhi Chen
Oct 2, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Scott M ThompsonDavid A Woodrum

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