Magnetic resonance-guided percutaneous cryoablation of uterine fibroids: early clinical experiences

Cardiovascular and Interventional Radiology
Yusuke SakuharaKazuo Miyasaka

Abstract

Uterine fibroids (leiomyomas) are the most common tumors of the uterus. The present study evaluated the feasibility and effectiveness of magnetic resonance (MR)-guided percutaneous cryoablation for uterine fibroids as a minimally invasive treatment alternative. From August 2001 to June 2002, MR-guided percutaneous cryoablation was performed on seven uterine fibroids in 6 patients who displayed clinical symptoms related to tumors. Using a horizontal-type open MR system, cryoablation probes were percutaneously placed in fibroids. Fibroids were ablated, and the site and size of ice balls were monitored on MR imaging. Postoperatively, patients completed a questionnaire to assess changes in presenting clinical symptoms, and MR images were obtained for all patients at follow-up. Changes in clinical symptoms and tumor volume were evaluated in each patient. All treated patients showed reductions in tumor size. Mean volume reduction rate was 40.3% at 6 weeks postoperatively, and 79.4% at 9-12 months. All patients reported fever after treatment. Surgical drainage was required for abscess in the probe channel in one patient, and transient liver damage occurred in another. Subjective symptoms improved in all patients except one who had mul...Continue Reading

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Citations

Feb 28, 2006·Cardiovascular and Interventional Radiology·Jean-Pierre Pelage
Sep 1, 2010·Seminars in Interventional Radiology·Justin P McWilliamsStephen T Kee
Jul 31, 2009·Journal of Biomechanical Engineering·Raghav GoelJohn C Bischof
Apr 27, 2013·La Presse médicale·Lobna Ouldamer, Isabelle De Jesus
Nov 15, 2011·Journal de gynécologie, obstétrique et biologie de la reproduction·L Ouldamer, H Marret
Dec 8, 2009·Magnetic Resonance Imaging Clinics of North America·Fiona M FennessyClare M Tempany
Apr 11, 2009·Seminars in Ultrasound, CT, and MR·Shu-Huei ShenClare Tempany
Mar 11, 2008·Radiologic Clinics of North America·Fiona M FennessyClare M Tempany
Dec 12, 2007·Techniques in Vascular and Interventional Radiology·Servet TatliStuart G Silverman
Dec 6, 2006·Techniques in Vascular and Interventional Radiology·Gary Siskin
Jan 26, 2008·Journal of Magnetic Resonance Imaging : JMRI·Paul R MorrisonServet Tatli

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