PMID: 9442584Jan 27, 1998Paper

Magnetic resonance imaging features of solitary inflammatory brain masses

Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging
R BakshiF H Hochberg

Abstract

Brain lesions in inflammatory diseases may present as solitary masses, prompting a biopsy. We present neuroimaging and histologic findings in five patients with solitary, inflammatory, demyelinating mass lesions located in the supratentorial white matter and gray-white junction. The patients presented with seizures, focal neurologic signs, and neuroimaging findings that indicated the possibility of a neoplasm. Computed tomography (CT) revealed enhancing, single hypodense lesions associated with mild or no mass effect. On MRI, the lesions were hypointense on T1-weighted images and hyperintense on T2-weighted images. Variable patterns of enhancement were noted on CT and MRI, including homogeneous/patchy (n = 3) and ring/nodular (n = 1) enhancement. There was no evidence of calcification or hemorrhage. Biopsies revealed a leukoencephalitis and demyelination, with varying degrees of demyelination among the cases. The syndrome, relating to a solitary lesion, was corticosteroid-sensitive, and it ultimately stabilized. Extensive longitudinal evaluations failed to reveal multiple sclerosis, infection, or neoplasm. Solitary inflammatory lesions add to the differential diagnosis of large, supratentorial, solitary space-occupying lesions ...Continue Reading

References

Dec 19, 1975·Acta Neuropathologica·T Kitamura
Apr 19, 1979·The New England Journal of Medicine·G E FeurleR Waldherr
Feb 1, 1979·Radiology·E R HeinzP Crumrine
Jun 11, 1992·AJR. American Journal of Roentgenology·R D TienP C Burger
Apr 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·B D YoulI F Moseley
Nov 1, 1990·Pediatric Neurology·M L ZupancC R Partington
Nov 22, 1990·The New England Journal of Medicine·E L LogigianA C Steere
Jan 1, 1987·Annals of Neurology·M AdamsE A Smuckler
Jun 1, 1986·Archives of Neurology·S M de la MonteE P Richardson
Nov 1, 1965·Archives of Neurology·L D Prockop, E R Heinz
Oct 1, 1982·Acta Neurologica Scandinavica·C M Poser
Jun 1, 1982·Neurology·J J HalperinG M Kleinman
Mar 1, 1983·Annals of Neurology·C M PoserW W Tourtellotte
Sep 1, 1982·Journal of Neurology, Neurosurgery, and Psychiatry·H J SagarM M Esiri
Mar 1, 1993·Archives of Neurology·R S McLachlanH Reichman
Jan 1, 1996·Journal of Neurology, Neurosurgery, and Psychiatry·L AldersonD N Louis
Jun 1, 1958·Neurology·T RASMUSSEND LLOYDSMITH

❮ Previous
Next ❯

Citations

Oct 22, 1998·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·R BakshiW R Kinkel
Dec 3, 2005·Multiple Sclerosis : Clinical and Laboratory Research·Stephen M Selkirk, Jiong Shi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Acute Hemorrhagic Leukoencephalitis

Acute hemorrhagic leukoencephalitis is a rare form of acute disseminated encephalomyelitis characterized by acute inflammation in the brain and spinal cord that causes demyelination and bleeding. It is often fatal, although treatment with immunosuppressives and plasma exchange can be helpful. Find the latest research on acute hemorrhagic leukoencephalitis here.

Related Papers

Korean Journal of Radiology : Official Journal of the Korean Radiological Society
H S KimS K Khang
Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
D LottiM Merlo
© 2021 Meta ULC. All rights reserved