Magnetic Resonance Imaging Findings following Intraarticular Infliximab Therapy for Refractory Temporomandibular Joint Arthritis among Children with Juvenile Idiopathic Arthritis

The Journal of Rheumatology
Matthew L StollRandy Q Cron

Abstract

To evaluate the involvement of intraarticular (IA) infliximab (IFX) in the management of temporomandibular joint (TMJ) arthritis associated with juvenile idiopathic arthritis (JIA) that is refractory to systemic treatment and IA corticosteroid therapy. Ours was a retrospective study of children with JIA who received IA IFX into the TMJ. The effectiveness of treatment on the progression of acute and chronic changes was assessed by a quantitative magnetic resonance imaging scoring system. Median acute and chronic scores worsened by 0.25 and 0.75, respectively. In multivariate analysis, worsening acute scores and passage of time predicted worsening of the chronic scores. IA IFX allowed for progression of refractory TMJ arthritis in most but not all children with JIA.

References

Aug 10, 2006·Current Opinion in Rheumatology·Bita Arabshahi, Randy Q Cron
Dec 21, 2006·AJR. American Journal of Roentgenology·Anne Marie CahillRichard B Towbin
Jan 24, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Matthew L StollRandy Q Cron
May 17, 2012·The Journal of Rheumatology·Matthew L StollRandy Q Cron
Oct 10, 2013·Arthritis Care & Research·Yoginder N VaidRandy Q Cron

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Citations

Nov 3, 2015·The Journal of Rheumatology·Rotraud K Saurenmann, Christian J Kellenberger
Apr 27, 2018·Pediatric Rheumatology Online Journal·Matthew L StollRandy Q Cron
Dec 13, 2019·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Paulo Goberlânio de Barros SilvaRamille Araújo Lima
Mar 9, 2021·Journal of the World Federation of Orthodontists·Chung How KauGregg H Gilbert
Mar 7, 2021·Diagnostics·Lauren CovertBenjamin L Hechler

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