Magnetic resonance imaging goes postmortem: noninvasive detection and assessment of myocardial infarction by postmortem MRI.

European Radiology
Christian JackowskiAnders Persson

Abstract

To investigate the performance of postmortem magnetic resonance imaging (pmMRI) in identification and characterization of lethal myocardial infarction in a non-invasive manner on human corpses. Before forensic autopsy, 20 human forensic corpses were examined on a 1.5-T system for the presence of myocardial infarction. Short axis, transversal and longitudinal long axis images (T1-weighted; T2-weighted; PD-weighted) were acquired in situ. In subsequent autopsy, the section technique was adapted to short axis images. Histological investigations were conducted to confirm autopsy and/or radiological diagnoses. Nineteen myocardial lesions were detected and age staged with pmMRI, of which 13 were histologically confirmed (chronic, subacute and acute). Six lesions interpreted as peracute by pmMRI showed no macroscopic or histological finding. Five of the six peracute lesions correlated well to coronary pathology, and one case displayed a severe hypertrophic alteration. pmMRI reliably demonstrates chronic, subacute and acute myocardial infarction in situ. In peracute cases pmMRI may display ischemic lesions undetectable at autopsy and routine histology. pmMRI has the potential to substantiate autopsy and to counteract the loss of reliab...Continue Reading

References

Jun 1, 1988·Forensic Science International : Synergy·M Varga, L Zsonda
Apr 9, 2002·The Medical Journal of Australia·Helen E WardMichael I Cleary
Apr 16, 2002·The American Journal of Forensic Medicine and Pathology·Alfredo Ribeiro-SilvaMarcos A Rossi
Dec 23, 2003·Forensic Science International : Synergy·Seiji ShiotaniYuji Itai
Mar 1, 2005·Forensic Science International : Synergy·Christian JackowskiRichard Dirnhofer
Jun 9, 2005·Forensic Science International : Synergy·Christian JackowskiMartin Sonnenschein
Dec 6, 2005·Quality & Safety in Health Care·K G ShojaniaL Goldman
Sep 16, 2006·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Richard DirnhoferMichael J Thali
Oct 5, 2006·Journal of Forensic Sciences·Christian JackowskiMichael J Thali
Mar 6, 2007·Forensic Science International : Synergy·Kathrin YenRichard Dirnhofer
Feb 29, 2008·The New England Journal of Medicine·Kaveh G Shojania, Elizabeth C Burton
Apr 24, 2008·AJR. American Journal of Roentgenology·Steffen RossErich Gygax
Mar 4, 2010·Current Problems in Cardiology·Amy M West, Christopher M Kramer

❮ Previous
Next ❯

Citations

Jan 17, 2013·International Journal of Legal Medicine·Katarzyna MichaudPatrice Mangin
May 14, 2014·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Steffen G RossPatricia M Flach
Nov 6, 2013·The British Journal of Radiology·T D RuderG M Hatch
Jun 21, 2013·Forensic Science, Medicine, and Pathology·Thomas D RuderPranitha Kamat
Jan 8, 2013·International Journal of Legal Medicine·Christine ChevallierGrabherr Silke
Dec 18, 2012·European Radiology·Christian JackowskiNicole Schwendener
Aug 3, 2013·European Radiology·Francesca R PluchinottaStephen P Sanders
Oct 2, 2012·Forensic Science International : Synergy·Nicole SchwendenerChristian Jackowski
Jun 23, 2012·Forensic Science International : Synergy·J-B ZerlauthS Grabherr
May 25, 2012·Forensic Science International : Synergy·C PalmiereS Grabherr
Apr 7, 2012·Forensic Science International : Synergy·Takahisa OkudaTomoya Kobayashi
Aug 2, 2011·Forensic Science International : Synergy·Christian JackowskiMorten Keller-Sutter
Nov 26, 2015·Legal Medicine·Garyfalia AmpanoziThomas D Ruder
Aug 19, 2015·Forensic Science International : Synergy·Jérôme BonzonChristian Jackowski
Apr 7, 2015·La Radiologia medica·Silke GrabherrPatrice Mangin
Feb 1, 2015·European Radiology·Wolf-Dieter ZechChristian Jackowski
Jul 5, 2011·European Journal of Radiology·Thomas D RuderGary M Hatch
Dec 10, 2013·Forensic Science International : Synergy·Claudia SchulzeChristian Jackowski
Sep 25, 2014·International Journal of Legal Medicine·Matteo PolaccoRiccardo Rossi
Mar 21, 2012·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Claes LundströmAnders Ynnerman
Feb 25, 2017·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Elizabeth Watson, Hock Gan Heng
May 5, 2018·Heart Failure Reviews·Benedetta GuidiMarco Di Paolo
Sep 7, 2019·Forensic Sciences Research·Katarzyna MichaudSilke Grabherr
Apr 21, 2021·European Radiology·Giovanni Donato AquaroFabio A Recchia

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.