Magnetic resonance imaging in early rheumatoid arthritis: a multicenter, prospective study

Clinical Rheumatology
Ru LiZhan-Guo Li

Abstract

To identify the magnetic resonance imaging (MRI) features of hands and wrists in early rheumatoid arthritis (RA). A total of 129 early arthritis patients (≤1 year) were enrolled in the study. At presentation, MRI of the hands was performed, with clinical and laboratory analyses. After a 1-year follow-up, clinical diagnosis of early RA or non-RA was confirmed by two rheumatologists. The characteristics of MRI variables at baseline in RA patients not fulfilling ACR 1987 criteria [RA-87(-)] were compared with those fulfilling ACR1987 criteria [RA-87(+)] and non-RA. In the 129 early arthritis patients, 90 were diagnosed with RA in a 1-year follow-up. There were 47.8 % (43/90) of the RA patients not fulfilling ACR 1987 criteria [RA-87(-)]. The scores of synovitis in RA-87(-) patients were similar with those in RA-87(+) [Synovitis score, 14.0 (IQR, 4.0-25.0) vs. 14.0 (IQR, 10.0-25.0), p > 0.05]. Compared with those in non-RA, RA-87(-) patients had higher synovitis scores and occurrence of synovitis in proximal interphalangeal (PIP) joints [synovitis score, 14.0 (IQR, 4.0-25.0) vs. 6.0 (IQR, 2.0-14.5), p = 0.046; occurrence of PIP synovitis: 53.5 vs. 27.3 %, p = 0.02]. There was no significant difference of bone marrow edema, bone ero...Continue Reading

References

Jul 9, 2003·Arthritis and Rheumatism·Maarten Boers
Jan 14, 2005·Annals of the Rheumatic Diseases·M ØstergaardP Conaghan
Mar 3, 2011·The Journal of Rheumatology·Henriëtte BaanMartin A F J van de Laar
May 11, 2011·Arthritis Care & Research·Lisa G SuterR Scott Braithwaite
Jun 11, 2011·Arthritis Research & Therapy·Paraskevi E KostaMaria I Argyropoulou

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Citations

Nov 15, 2018·Chinese Medical Journal·Zhan-Guo LiQi-Zhe Wu

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