PMID: 6397697Jan 1, 1984Paper

Magnetic resonance imaging (MRI): method and early clinical experiences in diseases of the central nervous system

Neurosurgical Review
W J Huk, G Gademann

Abstract

Magnetic resonance imaging (MRI) has undergone a rapid development which is still continuing. In this article a survey is given of the present status of this new diagnostic tool in the evaluation of diseases of the central nervous system. When atoms with uneven numbers of protons or neutrons in a homogeneous magnetic field are tilted against the main vector of this field by a radiofrequency pulse, nuclear magnetic resonance can be observed. During the relaxation of the little dipoles back to the direction of the underlying magnetic field, a resonance signal is generated. The superposition of variable field gradients enables the scanning of sectional images in the axial, frontal and sagittal plane. The variables of H+-magnetic resonance which can be utilized for imaging are: the proton density, the relaxation times T1 (spin-lattice) and T2 (spin-spin) and flow effects. While the proton density in organic tissue fluctuates only by some 10%, the relaxation times may vary by several hundred per cent. Tissue contrast, therefore, is mainly based on relaxation times differences. The image character can also be influenced by variations of imaging parameters (i.e. repetition rate, interpulse delay, read out or echo delay) in different i...Continue Reading

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Jan 1, 1993·Acta neurochirurgica·D BalériauxW O Bank
Sep 1, 1986·Clinical Radiology·R R MawhinneyB S Worthington
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Dec 10, 1988·International Journal of Technology Assessment in Health Care·E B Larson, D L Kent
Oct 8, 2020·Surgical Neurology International·Albert J FenoyAaron W Hocher

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